Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.45 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | NEK1 | Q96PY6 | 3/20 | 0.38 |
| ▸ | PLAU | P00749 | 2/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30760378 | 0.72 | ASH1L (0.54) | ASH1LPDK2AXLNEK1PLAU | |
| SCHEMBL16749656 | 0.67 | CA12 (0.58) | ASH1LPDK2AXLNEK1PLAU | |
| SCHEMBL30571550 | 0.67 | IL2 (0.49) | ASH1LPDK2AXLNEK1PLAU | |
| SCHEMBL26120622 | 0.67 | IL2 (0.49) | ASH1LPDK2AXLNEK1PLAU | |
| SCHEMBL7830361 | 0.67 | NR1H4 (0.57) | ASH1LPDK2AXLNEK1ERN1 | |
| SCHEMBL29279029 | 0.67 | ERN1 (0.51) | ASH1LPDK2AXLNEK1PLAU | |
| SCHEMBL67941 | 0.66 | CA12 (0.68) | PDK2PLAUERN1CA12CA1 | |
| SCHEMBL12777036 | 0.65 | CA12 (0.60) | PDK2NEK1PLAUERN1CA12 | |
| SCHEMBL30350436 | 0.65 | CA12 (0.60) | PDK2NEK1PLAUERN1CA12 | |
| SCHEMBL7823524 | 0.65 | RAB9A (0.48) | ASH1LPDK2AXLNEK1PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |