Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | ERN1 | O75460 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | AXL | P30530 | 1/20 | 0.55 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.54 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.54 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.54 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.54 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.54 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.53 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.53 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.53 |
| ▸ | CDK8 | P49336 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL67941 | 0.90 | CA12 (0.68) | CA12CA1CA2CA9ERN1 | |
| SCHEMBL27715902 | 0.88 | CA12 (0.71) | CA12CA1CA2CA9ERN1 | |
| SCHEMBL30760378 | 0.88 | ASH1L (0.54) | CA12CA1CA2CA9ERN1 | |
| SCHEMBL28755028 | 0.87 | TSHR (0.60) | CA12CA1CA2CA9ERN1 | |
| Methane SCHEMBL28667111 | 0.86 | TSHR (0.58) | CA12CA1CA2CA9ERN1 | |
| SCHEMBL6538289 | 0.85 | PLAU (0.54) | CA12CA1CA2CA9ERN1 | |
| SCHEMBL1221576 | 0.85 | TSHR (0.67) | CA12CA1CA2CA9ERN1 | |
| SCHEMBL29410906 | 0.85 | TSHR (0.67) | CA12CA1CA2CA9ERN1 | |
| SCHEMBL7830361 | 0.84 | NR1H4 (0.57) | CA12CA1CA2CA9ERN1 | |
| SCHEMBL6082886 | 0.84 | EGFR (0.57) | CA12CA1CA2CA9ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3514159-A1 | ALUMINIUM METAL ORGANIC FRAMEWORK MATERIAL | The Texas A&M University System (US) | 2019-07-24 | — | — | EP | disclosed |
| US-9724668-B2 | Iron metal organic framework materials | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2017-08-08 | — | — | US | disclosed |
| US-9724668-B2 | Iron metal organic framework materials | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2017-08-08 | — | — | US | disclosed |
| US-20160346759-A1 | Iron Metal Organic Framework Materials | U.S. DEPARTMENT OF ENERGY | 2016-12-01 | — | — | US | disclosed |
| US-20160346759-A1 | Iron Metal Organic Framework Materials | U.S. DEPARTMENT OF ENERGY | 2016-12-01 | — | — | US | disclosed |
| EP-2876112-B1 | Monocrystalline iron metal organic frameworks | TEXAS A & M UNIV SYS (US) | 2016-07-13 | — | — | EP | disclosed |
| US-9102691-B2 | Aluminum metal organic framework materials | TEXAS A&M UNIVERSITY SYSTEM (US) | 2015-08-11 | — | — | US | disclosed |
| US-9102691-B2 | Aluminum metal organic framework materials | TEXAS A&M UNIVERSITY SYSTEM (US) | 2015-08-11 | — | — | US | disclosed |
| US-20150152123-A1 | Aluminum Metal Organic Framework Materials | U.S. DEPARTMENT OF ENERGY | 2015-06-04 | — | — | US | disclosed |
| WO-2015079230-A1 | ALUMINIUM METAL ORGANIC FRAMEWORK MATERIALS | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2015-06-04 | — | — | WO | disclosed |
| US-20150152123-A1 | Aluminum Metal Organic Framework Materials | U.S. DEPARTMENT OF ENERGY | 2015-06-04 | — | — | US | disclosed |
| EP-2876112-A1 | Monocrystalline iron metal organic frameworks | THE TEXAS A & M UNIVERSITY SYSTEM (US) | 2015-05-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160346759-A1 | Iron Metal Organic Framework Materials | TFRC, FTH1, FECH | CA12 321/4885CA1 514/4885CA2 405/4885 |
| US-20150152123-A1 | Aluminum Metal Organic Framework Materials | AS3MT, ORAI2, ORAI3 | CA12 284/4885CA1 94/4885CA2 113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.