Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | PRF1 | P14222 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | WEE1 | P30291 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16602007 | 0.88 | MCL1 (0.56) | MCL1BRD4PRF1ACHEPDCD1 | |
| SCHEMBL16602049 | 0.84 | MCL1 (0.50) | MCL1 | |
| SCHEMBL16602014 | 0.80 | MCL1 (0.43) | MCL1CHEK1 | |
| SCHEMBL16602019 | 0.78 | MCL1 (0.53) | MCL1 | |
| SCHEMBL16601998 | 0.76 | MCL1 (0.47) | MCL1CHEK1 | |
| SCHEMBL16601996 | 0.75 | MCL1 (0.52) | MCL1BRD4PRF1CHEK1WEE1 | |
| SCHEMBL16602005 | 0.75 | MCL1 (0.43) | MCL1WEE1 | |
| SCHEMBL16602011 | 0.73 | MCL1 (0.57) | MCL1 | |
| SCHEMBL16602018 | 0.73 | ALDH1A1 (0.36) | BRD4 | |
| SCHEMBL16602048 | 0.72 | MCL1 (0.53) | MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |