Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.56 |
| ▸ | PRF1 | P14222 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16602019 | 0.90 | MCL1 (0.53) | MCL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16602012 | 0.89 | MCL1 (0.52) | MCL1PRKDC | |
| SCHEMBL16601994 | 0.88 | MCL1 (0.49) | MCL1PRF1ACHEPDCD1CD274 | |
| SCHEMBL16602011 | 0.86 | MCL1 (0.57) | MCL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16602008 | 0.79 | MCL1 (0.55) | MCL1PRF1BRD4 | |
| SCHEMBL16602004 | 0.77 | MCL1 (0.52) | MCL1RXRARXRB | |
| SCHEMBL14922765 | 0.74 | MCL1 (0.67) | MCL1CYP1A2 | |
| SCHEMBL16602049 | 0.73 | MCL1 (0.50) | MCL1 | |
| SCHEMBL16601998 | 0.73 | MCL1 (0.47) | MCL1RXRARXRB | |
| SCHEMBL2367407 | 0.73 | MCL1 (1.00) | MCL1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |