Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 3/20 | 0.56 |
| ▸ | AXL | P30530 | 3/20 | 0.54 |
| ▸ | KMO | O15229 | 2/20 | 0.53 |
| ▸ | DDT | P30046 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 2/20 | 0.47 |
| ▸ | RXRB | P28702 | 2/20 | 0.47 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.46 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | LDHB | P07195 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.43 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.43 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.43 |
| ▸ | CD74 | P04233 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | PLK4 | O00444 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12556925 | 0.80 | NPC1 (0.50) | MAP4K4AXLIKBKETBK1PLK4 | |
| SCHEMBL16602023 | 0.79 | KMO (0.61) | MAP4K4KMORXRARXRB | |
| SCHEMBL14758859 | 0.76 | KMO (0.58) | MAP4K4AXLKMODDTRXRA | |
| SCHEMBL16601738 | 0.76 | MAP4K4 (0.56) | MAP4K4AXLNTRK1FYNDYRK1A | |
| SCHEMBL71238 | 0.76 | KMO (0.86) | KMORXRARXRBCD74MIF | |
| SCHEMBL30725957 | 0.76 | KMO (0.86) | KMORXRARXRBCD74MIF | |
| SCHEMBL29904709 | 0.76 | KMO (0.86) | KMORXRARXRBCD74MIF | |
| SCHEMBL29911642 | 0.75 | KMO (0.74) | MAP4K4AXLKMODDTRXRA | |
| SCHEMBL29725579 | 0.75 | KMO (0.74) | MAP4K4AXLKMODDTRXRA | |
| SCHEMBL15764214 | 0.75 | PTPRC (0.70) | KMORXRARXRBCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |