Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2524106 | 0.90 | GPR119 (0.84) | GPR119KCNH2 | |
| SCHEMBL12213563 | 0.85 | GPR119 (0.77) | GPR119KCNH2 | |
| SCHEMBL2521779 | 0.81 | GPR119 (1.00) | GPR119KCNH2 | |
| SCHEMBL2518871 | 0.81 | GPR119 (0.83) | GPR119KCNH2 | |
| SCHEMBL14845359 | 0.80 | GPR119 (0.73) | GPR119KCNH2 | |
| SCHEMBL2518258 | 0.80 | GPR119 (0.85) | GPR119KCNH2 | |
| SCHEMBL2522929 | 0.80 | GPR119 (0.85) | GPR119KCNH2 | |
| SCHEMBL2522695 | 0.75 | GPR119 (1.00) | GPR119KCNH2 | |
| SCHEMBL2516235 | 0.73 | GPR119 (1.00) | GPR119KCNH2 | |
| SCHEMBL2335281 | 0.72 | GPR119 (1.00) | GPR119KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2556069-B1 | 4-(1-(PYRIMIDIN-2-YL)PIPERIDIN-4-YLOXY)PYRIDIN-2-ONE COMPOUNDS AS GPR119 MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2015-04-01 | — | — | EP | disclosed |