Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 5/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1660547 | 1.00 | C3AR1 (0.46) | C3AR1EPHX2CCR3RPS6KB1TLR2 | |
| SCHEMBL21722104 | 0.90 | C3AR1 (0.46) | C3AR1EPHX2RPS6KB1TLR2 | |
| Arginine SCHEMBL12002430 | 0.88 | FOLH1 (0.39) | C3AR1FOLH1 | |
| Arginine SCHEMBL1662071 | 0.88 | FOLH1 (0.39) | C3AR1FOLH1 | |
| Arginine SCHEMBL1660453 | 0.88 | FOLH1 (0.39) | C3AR1FOLH1 | |
| Arginine SCHEMBL1663212 | 0.88 | FOLH1 (0.39) | C3AR1FOLH1 | |
| SCHEMBL11125240 | 0.85 | C3AR1 (0.48) | C3AR1EPHX2FOLH1 | |
| SCHEMBL6331670 | 0.78 | C3AR1 (0.45) | C3AR1TLR2FOLH1 | |
| SCHEMBL6331668 | 0.78 | C3AR1 (0.45) | C3AR1TLR2FOLH1 | |
| SCHEMBL29697124 | 0.78 | C3AR1 (0.52) | C3AR1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2491051-A2 | GADD45BETA TARGETING AGENTS | Imperial Innovations Limited (GB) | 2012-08-29 | — | — | EP | claimed |
| WO-2011048390-A2 | GADD45BETA TARGETING AGENTS | IMPERIAL INNOVATIONS LIMITED (GB) | 2011-04-28 | — | — | WO | claimed |