Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1660342 | 0.90 | C3AR1 (0.46) | C3AR1EPHX2TLR2RPS6KB1 | |
| SCHEMBL1660547 | 0.90 | C3AR1 (0.46) | C3AR1EPHX2TLR2RPS6KB1 | |
| SCHEMBL11125240 | 0.85 | C3AR1 (0.48) | C3AR1EPHX2MTNR1AMTNR1BITGB3 | |
| SCHEMBL20988216 | 0.80 | NOD1 (0.35) | C3AR1NPY1RITGB3ITGA2B | |
| Arginine SCHEMBL1663212 | 0.79 | FOLH1 (0.39) | C3AR1 | |
| Arginine SCHEMBL1662071 | 0.79 | FOLH1 (0.39) | C3AR1 | |
| Arginine SCHEMBL1660453 | 0.79 | FOLH1 (0.39) | C3AR1 | |
| Arginine SCHEMBL12002430 | 0.79 | FOLH1 (0.39) | C3AR1 | |
| SCHEMBL19090970 | 0.79 | NPY4R (0.35) | C3AR1EPHX2NPY1RITGB3ITGA2B | |
| SCHEMBL28573562 | 0.79 | NOD1 (0.34) | C3AR1NPY1RITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020034209-A1 | AMINO ACID DEHYDROGENASE MUTANT AND APPLICATION THEREOF | 凯莱英生命科学技术(天津)有限公司 | 2020-02-20 | — | — | WO | disclosed |