SCHEMBL16604255

SCHEMBL16604255

COCCN1CCN2CCOCCOCCN(CCOCCOCC2)CC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.45
ALDH1A1 P00352 2/20 0.44
KDM4E B2RXH2 1/20 0.44
SYK P43405 1/20 0.40
MAPK1 P28482 2/20 0.37
CYP1A2 P05177 1/20 0.37
CHRM2 P08172 1/20 0.37
CHRM1 P11229 1/20 0.37
HTR2A P28223 1/20 0.37
SCN1A P35498 1/20 0.37
HTR2B P41595 1/20 0.37
KCNH2 Q12809 1/20 0.37
SCN2A Q99250 1/20 0.37
SIGMAR1 Q99720 1/20 0.37
SCN3A Q9NY46 1/20 0.37
HRH3 Q9Y5N1 1/20 0.37
POLB P06746 1/20 0.36
HSD11B1 P28845 1/20 0.36
CYP2D6 P10635 1/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11204275 0.88 TDP1 (0.54) TDP1ALDH1A1KDM4ESYKMAPK1
SCHEMBL9099366 0.88 TDP1 (0.54) TDP1ALDH1A1KDM4ESYKMAPK1
SCHEMBL81823 0.86 TDP1 (0.56) TDP1ALDH1A1KDM4ESYKMAPK1
SCHEMBL12137196 0.82 TDP1 (0.50) TDP1ALDH1A1KDM4ESYKMAPK1
SCHEMBL4608545 0.82 TDP1 (0.46) TDP1ALDH1A1KDM4ESYKMAPK1
SCHEMBL28383716 0.80 TDP1 (0.51) TDP1ALDH1A1KDM4ESYKMAPK1
SCHEMBL6057032 0.78
SCHEMBL8149011 0.78 HSD11B1 (0.47) TDP1ALDH1A1KDM4ESIGMAR1POLB
SCHEMBL3142504 0.78 TDP1 (0.50) TDP1ALDH1A1KDM4ESYKMAPK1
SCHEMBL4893194 0.78 HSD11B1 (0.47) TDP1ALDH1A1KDM4ESIGMAR1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9362542-B2 Lithium ion battery components with chelating agents having oriented permanent dipole moments GM Global Technology Operations LLC (US) 2016-06-07 US disclosed
US-9362542-B2 Lithium ion battery components with chelating agents having oriented permanent dipole moments GM Global Technology Operations LLC (US) 2016-06-07 US disclosed
US-20150093628-A1 LITHIUM ION BATTERY COMPONENTS WITH CHELATING AGENTS HAVING ORIENTED PERMANENT DIPOLE MOMENTS GM Global Technology Operations LLC 2015-04-02 US disclosed
US-20150093628-A1 LITHIUM ION BATTERY COMPONENTS WITH CHELATING AGENTS HAVING ORIENTED PERMANENT DIPOLE MOMENTS GM Global Technology Operations LLC 2015-04-02 US disclosed