SCHEMBL81823

SCHEMBL81823

COCCN1CCOCC1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.56
SYK P43405 1/20 0.49
ALDH1A1 P00352 2/20 0.46
KEAP1 Q14145 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
KDM4E B2RXH2 1/20 0.46
MAPK1 P28482 2/20 0.46
CYP1A2 P05177 1/20 0.46
CHRM2 P08172 1/20 0.46
CHRM1 P11229 1/20 0.46
HTR2A P28223 1/20 0.46
SCN1A P35498 1/20 0.46
HTR2B P41595 1/20 0.46
KCNH2 Q12809 1/20 0.46
SCN2A Q99250 1/20 0.46
SIGMAR1 Q99720 1/20 0.46
SCN3A Q9NY46 1/20 0.46
HRH3 Q9Y5N1 1/20 0.46
POLB P06746 1/20 0.45
CYP2D6 P10635 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11204275 0.98 TDP1 (0.54) TDP1SYKALDH1A1KEAP1SMN1; SMN2
SCHEMBL9099366 0.98 TDP1 (0.54) TDP1SYKALDH1A1KEAP1SMN1; SMN2
SCHEMBL28383716 0.94 TDP1 (0.51) TDP1SYKALDH1A1KEAP1SMN1; SMN2
SCHEMBL12137196 0.92 TDP1 (0.50) TDP1SYKALDH1A1KEAP1SMN1; SMN2
SCHEMBL3142504 0.92 TDP1 (0.50) TDP1SYKALDH1A1KEAP1SMN1; SMN2
SCHEMBL4608545 0.87 TDP1 (0.46) TDP1SYKALDH1A1KEAP1SMN1; SMN2
SCHEMBL92600 0.87 TSHR (0.53) TDP1SYKALDH1A1KEAP1SMN1; SMN2
SCHEMBL11428304 0.87 TSHR (0.53) TDP1SYKALDH1A1KEAP1SMN1; SMN2
SCHEMBL501602 0.87 TSHR (0.53) TDP1SYKALDH1A1KEAP1SMN1; SMN2
SCHEMBL20280727 0.87 TSHR (0.53) TDP1SYKALDH1A1KEAP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1692 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260055619-A1 WATERPROOF ADHESIVE COMPOSITIONS AND FLOORING SYSTEMS DICKENS CARROLL BENFORD (US) 2026-02-26 US claimed
CN-119799151-A Polyurethane coating for road marking and preparation method thereof 万华化学集团股份有限公司 2025-04-11 CN claimed
US-11845830-B2 Method for producing a composition comprising a polyurethane with NCO end groups BOSTIK SA (FR) 2023-12-19 US claimed
CN-117229717-A Chemical mechanical polishing solution and preparation method and application thereof 上海集成电路材料研究院有限公司 2023-12-15 CN claimed
CN-117229716-A Application of morpholine-ring-containing water-soluble small molecules and chemical mechanical polishing solution 上海集成电路材料研究院有限公司 2023-12-15 CN claimed
WO-2023225359-A1 ANTIBODY-DRUG CONJUGATES OF ANTINEOPLASTIC COMPOUNDS AND METHODS OF USE THEREOF NOVARTIS AG (CH) 2023-11-23 WO claimed
CN-111491930-B Substituted Indole Compounds Useful as TLR Inhibitors 百时美施贵宝公司 2023-09-26 CN claimed
US-20230212445-A1 WATERPROOF ADHESIVE COMPOSITIONS DICKENS CARROLL BENFORD (US) 2023-07-06 US claimed
EP-3161029-B1 PYRROLIDINE-BASED CATALYSTS FOR USE IN POLYURETHANE MATERIALS HUNTSMAN PETROCHEMICAL LLC (US) 2023-01-11 EP claimed
CN-111517922-B Method for preparing 4-chloro-3,5-dimethylphenol 万华化学集团股份有限公司 2022-11-04 CN claimed
US-5153232-A FOAMED POLYUREA ELASTOMER-RIGID AND CLOSE-CELLED TEXACO INC. (US) 1992-10-06 US claimed
EP-0494546-A1 Foamed polyurea elastomer Huntsman Corporation (US) 1992-07-15 EP claimed
EP-0476785-A1 Processes for the preparation of aminoethers OSi Specialties, Inc. (US) 1992-03-25 EP claimed
US-4615771-A ENTRAINMENT TEXACO INC. (US) 1986-10-07 US claimed
US-4579630-A DISTILLING A MIXTURE HAVING CLOSE BOILING POINTS WITH AN ENTRAINER TEXACO INC. (US) 1986-04-01 US claimed
US-4552958-A Method of separating primary amines from tertiary amines using non-polar hydrocarbon solvent and water TEXACO INC. (US) 1985-11-12 US claimed
US-4552957-A SOLVENT EXTRACTION TEXACO INC. (US) 1985-11-12 US claimed
US-4299957-A REACTING N-(2-HYDROXYETHYL)MORPHOLINE WITH EXCESS OF METHANOL IN PRESENCE OF A SILICA-ALUMINUM CATALYST TEXACO INC. (US) 1981-11-10 US claimed
US-4299956-A REACTING N-2-HYDROXYETHYL MORPHOLINE WITH A PHOSPHOROUS CONTAINING CATALYST TEXACO INC. (US) 1981-11-10 US claimed
US-4228248-A Morpholine derivatives and use as polyurethane catalyst TEXACO DEVELOPMENT CORP. (US) 1980-10-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260055619-A1 WATERPROOF ADHESIVE COMPOSITIONS AND FLOORING SYSTEMS TLN1, L1CAM, CDH1 TDP1 2479/4885SYK 3803/4885ALDH1A1 3130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.