SCHEMBL1660464

SCHEMBL1660464

C=Cc1cccc(CF)c1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
ALDH1A1 P00352 2/20 0.42
TSHR P16473 1/20 0.42
FAAH O00519 1/20 0.38
MEN1 O00255 1/20 0.33
POLB P06746 1/20 0.33
KMT2A Q03164 1/20 0.33
PTGS2 P35354 1/20 0.33
HDAC8 Q9BY41 1/20 0.32
NFE2L2 Q16236 1/20 0.32
MAOA P21397 2/20 0.30
MAOB P27338 2/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20457810 0.83 TP53 (0.45) TP53TDP1ALDH1A1TSHRFAAH
SCHEMBL595537 0.82 TP53 (0.52) TP53TDP1ALDH1A1TSHRFAAH
SCHEMBL595016 0.82 TP53 (0.52) TP53TDP1ALDH1A1TSHRFAAH
SCHEMBL29375309 0.82 TP53 (0.52) TP53TDP1ALDH1A1TSHRFAAH
SCHEMBL1645656 0.80 TP53 (0.50) TP53TDP1ALDH1A1TSHRFAAH
SCHEMBL29619562 0.80 TP53 (0.50) TP53TDP1ALDH1A1TSHRFAAH
SCHEMBL249303 0.80 TP53 (0.50) TP53TDP1ALDH1A1TSHRFAAH
SCHEMBL28218123 0.79 TP53 (0.45) TP53TDP1ALDH1A1TSHRFAAH
SCHEMBL1023182 0.78 TP53 (0.48) TP53TDP1ALDH1A1TSHRFAAH
SCHEMBL4386462 0.78 TP53 (0.48) TP53TDP1ALDH1A1TSHRFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110698578-B Process for preparing blends of ultrahigh molecular weight polyolefins and low molecular weight polyolefins 宁波大学 2021-11-23 CN claimed
CN-110698578-A Process for preparing blends of ultrahigh molecular weight polyolefins and low molecular weight polyolefins 宁波大学 2020-01-17 CN claimed
CN-106084101-B A kind of preparation method of low entanglement polyethylene 宁波大学 2018-08-10 CN claimed
CN-106084101-A A kind of preparation method of low entanglement polyethylene 宁波大学 2016-11-09 CN claimed
US-4756989-A Aluminum or silicon substrate, copolymer resist layer comprising vinyl aromatic, ethylenically unsaturated units ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-07-12 US claimed
CN-120005311-A Polyethylene composition, polyethylene article and method of making the same 中国石油化工股份有限公司 2025-05-16 CN disclosed
CN-118159582-A Polymer, method for producing same, resin composition, and electronic component 日本瑞翁株式会社 2024-06-07 CN disclosed
CN-117836339-A Resin composition 日本瑞翁株式会社 2024-04-05 CN disclosed
CN-117024333-A Oxime ether compound containing styryl and preparation method and application thereof 贵州大学 2023-11-10 CN disclosed
CN-116745332-A Resin composition 日本瑞翁株式会社 2023-09-12 CN disclosed
CN-110698578-B Process for preparing blends of ultrahigh molecular weight polyolefins and low molecular weight polyolefins 宁波大学 2021-11-23 CN disclosed
CN-107614555-B Method for producing thermoplastic elastomer and thermoplastic elastomer 株式会社钟化 2020-03-20 CN disclosed
CN-110698578-A Process for preparing blends of ultrahigh molecular weight polyolefins and low molecular weight polyolefins 宁波大学 2020-01-17 CN disclosed
CN-104812790-B Organopolysiloxane graft polymers 花王株式会社 2019-04-12 CN disclosed
CN-106084101-B A kind of preparation method of low entanglement polyethylene 宁波大学 2018-08-10 CN disclosed
CN-106084101-A A kind of preparation method of low entanglement polyethylene 宁波大学 2016-11-09 CN disclosed
EP-2197857-B1 INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES DOW AGROSCIENCES LLC (US) 2013-03-06 EP disclosed
EP-2307394-A2 NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME Amorepacific Corporation (KR) 2011-04-13 EP disclosed
WO-2010002209-A2 NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AMOREPACIFIC CORPORATION (KR) 2010-01-07 WO disclosed
US-4756989-A Aluminum or silicon substrate, copolymer resist layer comprising vinyl aromatic, ethylenically unsaturated units ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-07-12 US disclosed