SCHEMBL249303

SCHEMBL249303

[CH2]Cc1cccc(C=C)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
FAAH O00519 1/20 0.44
ALDH1A1 P00352 3/20 0.44
TSHR P16473 1/20 0.44
MEN1 O00255 1/20 0.40
POLB P06746 1/20 0.40
KMT2A Q03164 1/20 0.40
HDAC8 Q9BY41 1/20 0.33
PTGS2 P35354 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.31
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
TRPA1 O75762 1/20 0.31
KDM4E B2RXH2 1/20 0.30
PKM P14618 1/20 0.30
PARP1 P09874 1/20 0.30
OPRM1 P35372 1/20 0.30
OPRD1 P41143 1/20 0.30
OPRK1 P41145 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL595537 0.84 TP53 (0.52) TP53TDP1FAAHALDH1A1TSHR
SCHEMBL29375309 0.84 TP53 (0.52) TP53TDP1FAAHALDH1A1TSHR
SCHEMBL595016 0.84 TP53 (0.52) TP53TDP1FAAHALDH1A1TSHR
SCHEMBL1645656 0.82 TP53 (0.50) TP53TDP1FAAHALDH1A1TSHR
SCHEMBL29619562 0.82 TP53 (0.50) TP53TDP1FAAHALDH1A1TSHR
SCHEMBL3669286 0.80 TP53 (0.48) TP53TDP1FAAHALDH1A1TSHR
SCHEMBL49633 0.80 TP53 (0.48) TP53TDP1FAAHALDH1A1TSHR
SCHEMBL184159 0.80 TDP1 (0.48) TP53TDP1FAAHALDH1A1TSHR
SCHEMBL1646925 0.80 TP53 (0.48) TP53TDP1FAAHALDH1A1TSHR
SCHEMBL1023182 0.80 TP53 (0.48) TP53TDP1FAAHALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 298 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5098981-A POLYORGANOSILOXANE CHISSO CORPORATION (JP) 1992-03-24 US claimed
EP-0349920-A2 Polyorganosiloxane Chisso Corporation (JP) 1990-01-10 EP claimed
CN-114981329-B Radiation polymerizable composition, cured layer thereof, optical fiber containing cured layer and production method thereof 日本精涂层株式会社 2024-06-21 CN disclosed
WO-2024113195-A1 A SOLID PARTICLE OF ORGANOSILICON-FUNCTIONAL CO-POLYMER, MANUFACTURING PROCESSTHEREOF, AND COSMETICS COMPRISING SAID SOLID PARTICLE DOW TORAY CO., LTD. (JP) 2024-06-06 WO disclosed
EP-3435962-B1 DEVICE FOR APPLYING A COMPOSITION IN THE FORM OF AN EMULSION COMPRISING A FILM-FORMING AGENT AND NON-VOLATILE OILS OREAL (FR) 2024-05-22 EP disclosed
CN-113164793-B Polymer blends for personal care formulations 陶氏环球技术有限责任公司 2024-05-17 CN disclosed
EP-3435963-B1 EMULSION COMPRISING A FILM-FORMING AGENT AND NON-VOLATILE OILS AND COSMETIC PROCESS OREAL (FR) 2024-05-01 EP disclosed
US-20240059811-A1 MONOMER COMPOSITION AND METHOD FOR PRODUCING SAME, AND COSMETIC OR COSMETIC RAW MATERIAL INCLUDING MONOMER COMPOSITION DOW TORAY CO LTD (JP) 2024-02-22 US disclosed
US-20240009088-A1 FILM-FORMING COMPOSITION FOR SKIN KAO CORPORATION (JP) 2024-01-11 US disclosed
US-20240000693-A1 RADICAL COPOLYMER COMPOSITION, PRODUCTION METHOD THEREFOR, AND COSMETIC OR COSMETIC INGREDIENT CONTAINING RADICAL COPOLYMER COMPOSITION DOW TORAY CO LTD (JP) 2024-01-04 US disclosed
CN-112512497-B Method for improving wrinkles of skin 花王株式会社 2023-12-22 CN disclosed
EP-1095953-A2 Silicone-grafted vinyl copolymer emulsion composition Dow Corning Toray Silicone Company, Ltd. (JP) 2001-05-02 EP disclosed
EP-1055674-A1 BRANCHED SILOXANE/SILALKYLENE COPOLYMER, SILICONE-CONTAINING ORGANIC POLYMER, AND PROCESS FOR PRODUCING THE SAME Dow Corning Toray Silicone Company, Ltd. (JP) 2000-11-29 EP disclosed
EP-1013702-A2 Gas-permeable film Dow Corning Toray Silicone Company, Ltd. (JP) 2000-06-28 EP disclosed
EP-1013736-A2 Water repellent for treating solids Dow Corning Toray Silicone Company, Ltd. (JP) 2000-06-28 EP disclosed
EP-1011033-A2 Carrier, toner and electrophotographic photoreceptor comprising a carbosiloxane dendrimer-functional vinyl type polymer Dow Corning Toray Silicone Company, Ltd. (JP) 2000-06-21 EP disclosed
EP-1006165-A2 Coating material Dow Corning Toray Silicone Company, Ltd. (JP) 2000-06-07 EP disclosed
EP-0963751-A2 Cosmetic raw material, cosmetic product, and method for manufacturing cosmetic raw material Dow Corning Toray Silicone Company, Ltd. (JP) 1999-12-15 EP disclosed
US-5098981-A POLYORGANOSILOXANE CHISSO CORPORATION (JP) 1992-03-24 US disclosed
EP-0349920-A2 Polyorganosiloxane Chisso Corporation (JP) 1990-01-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240059811-A1 MONOMER COMPOSITION AND METHOD FOR PRODUCING SAME, AND COSMETIC OR COSMETIC RAW MATERIAL INCLUDING MONOMER COMPOSITION NOTUM, CUTA, NOS1 TP53 1441/4885TDP1 420/4885FAAH 1282/4885
US-20240000693-A1 RADICAL COPOLYMER COMPOSITION, PRODUCTION METHOD THEREFOR, AND COSMETIC OR COSMETIC INGREDIENT CONTAINING RADICAL COPOLYMER COMPOSITION NOTUM, WEE1, FAR1 TP53 1102/4885TDP1 2323/4885FAAH 3030/4885
US-20240009088-A1 FILM-FORMING COMPOSITION FOR SKIN CUTA, FLNB, FLNA TP53 3348/4885TDP1 1201/4885FAAH 730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.