Sugi Predict

Sugi Predict / Compounds / SCHEMBL166047

SCHEMBL166047

SCHEMBL166047

CCC(C(=O)O)C(=O)C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 1/20 0.35
▸ FAAH O00519 6/20 0.33
▸ EPHX1 P07099 1/20 0.33
▸ CHRM1 P11229 1/20 0.33
▸ AKR1A1 P14550 1/20 0.33
▸ CHRM3 P20309 1/20 0.33
▸ HTR2A P28223 1/20 0.33
▸ HTR2C P28335 1/20 0.33
▸ ADRA1A P35348 1/20 0.33
▸ HRH1 P35367 1/20 0.33
▸ DRD3 P35462 1/20 0.33
▸ SLC6A3 Q01959 1/20 0.33
▸ HDAC1 Q13547 1/20 0.33
▸ HDAC2 Q92769 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ CA2 P00918 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ CES1 P23141 4/20 0.32
▸ GPR84 Q9NQS5 2/20 0.32
▸ SLC1A3 P43003 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL596376 0.86 FAAH (0.34) FAAHEPHX1CES1CES2MEN1
SCHEMBL596375 0.84 MAPT (0.32) MAPT
SCHEMBL596374 0.83 — —
SCHEMBL27760921 0.83 EPHX1 (0.32) FAAHEPHX1CES1CES2MEN1
SCHEMBL28961249 0.81 EPHX1 (0.31) FAAHEPHX1CES1CES2MEN1
SCHEMBL615588 0.81 EPHX1 (0.31) FAAHEPHX1CES1CES2MEN1
SCHEMBL27872575 0.81 EPHX1 (0.31) FAAHEPHX1CES1CES2MEN1
SCHEMBL27445268 0.81 EPHX1 (0.31) FAAHEPHX1CES1CES2MEN1
SCHEMBL499963 0.81 CHRM1 (0.46) MAPTFAAHEPHX1CHRM1AKR1A1
SCHEMBL19566 0.81 SLC1A3 (0.34) MAPTCHRM1AKR1A1CHRM3HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024209278-A1 A PROCESS FOR THE PREPARATION OF PYROXASULFONE GHARDA CHEMICALS LIMITED (IN) 2024-10-10 — — WO claimed
US-11434371-B2 Room temperature storage-stable UV/VIS and moisture dual curable polysiloxane composition DOW SILICONES CORPORATION (US) 2022-09-06 — — US claimed
WO-2022072417-A1 PERFORMANCE IMPROVEMENTS OF SILICON-DOMINANT ANODE CONTAINING LITHIUM ION BATTERIES THROUGH THE USE OF FLUORINATED ESTERS/CARBONATES/AROMATIC COMPOUNDS AND MULTIPLE ADDITIVE COMBINATION CONTAINING ELECTROLYTES ENEVATE CORPORATION (US) 2022-04-07 — — WO claimed
US-20220109146-A1 PERFORMANCE IMPROVEMENTS OF SILICON-DOMINANT ANODE CONTAINING LITHIUM ION BATTERIES THROUGH THE USE OF FLUORINATED ESTER/CARBONATES/AROMATIC COMPOUNDS AND MULTIPLE ADDITIVE COMBINATION CONTAINING ELECTROLYTES ENEVATE CORPORATION 2022-04-07 — — US claimed
US-20210139703-A1 ROOM TEMPERATURE STORAGE-STABLE UV/VIS AND MOISTURE DUAL CURABLE POLYSILOXANE COMPOSITION DOW SILICONES CORPORATION 2021-05-13 — — US claimed
EP-1254192-B1 ORGANOSILOXANE COMPOSITIONS DOW CORNING SA (BE) 2004-08-04 — — EP claimed
EP-1174415-B1 High purity preparation of fluorinated 1,3-dicarbonyls using BDM (bis-fluoroxydifluoromethane) AIR PROD & CHEM (US) 2003-10-22 — — EP claimed
EP-1174415-A1 High purity preparation of fluorinated 1,3-dicarbonyls using BDM (bis-fluoroxydifluoromethane) AIR PRODUCTS AND CHEMICALS, INC. (US) 2002-01-23 — — EP claimed
US-6307105-B1 ELECTROPHILICALLY FLUORINATING A BETA-DICARBONYL WITH BIS(FLUOROXY)DIFLUOROMETHANE IN THE PRESENCE OF AN ACID AIR PRODUCTS AND CHEMICALS, INC. 2001-10-23 — — US claimed
EP-0546669-B1 Preparation of fluorine-doped tungstic oxide and glass coating process FORD MOTOR CO (GB) 1996-04-17 — — EP claimed
US-5385751-A Atmospheric pressure CVD process for preparing fluorine-doped tungsten oxide films FORD MOTOR COMPANY (US) 1995-01-31 — — US claimed
US-5286520-A Reacting tungsten hexafluoride, an oxygen containing compound and a fluorine containing compound FORD MOTOR COMPANY (US) 1994-02-15 — — US claimed
EP-0546669-A1 Preparation of fluorine-doped tungstic oxide and glass coating process FORD MOTOR COMPANY LIMITED (GB) 1993-06-16 — — EP claimed
US-4883904-A Process for the preparation of ethyltrifluoroacetoacetate RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1989-11-28 — — US claimed
US-4590096-A USING ORGANOTIN COMPOUND AND ORGANIC FLUORINE DOPANT-CONTROLLING HUMIDITY OF CARRIER GAS STREAM M&T CHEMICALS INC. (US) 1986-05-20 — — US claimed
US-20250129031-A1 1,2,3-TRIAZOLE CARBONYL SULFONYLAMIDE COMPOUNDS AND USE THEREOF PI INDUSTRIES LTD (IN) 2025-04-24 — — US disclosed
EP-4469442-A1 1,2,3-TRIAZOLE CARBONYL SULFONYLAMIDE COMPOUNDS AND USE THEREOF PI Industries Ltd. (IN) 2024-12-04 — — EP disclosed
US-4546186-A 1,4,5,6,7,8-Hexahydro-2-methyl-5-oxo-4-(2-thiazolyl)-3-quinoline carboxylic acid 2-methyl(phenylmethyl)amino ethyl ester and pharmaceutically acceptable salts AMERICAN HOME PRODUCTS CORPORATION (US) 1985-10-08 — — US disclosed
EP-0096214-A1 Antibacterial pyrimidine compounds THE WELLCOME FOUNDATION LIMITED (GB) 1983-12-21 — — EP disclosed
EP-0055061-A1 Male gametocide method in small grain plants UNION CARBIDE CORPORATION (US) 1982-06-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129031-A1 1,2,3-TRIAZOLE CARBONYL SULFONYLAMIDE COMPOUNDS AND USE THEREOF GLP1R, CBR3, CBR1 MAPT 3579/4885FAAH 984/4885EPHX1 1501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.