Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166047 | 0.81 | MAPT (0.35) | SLC1A3SLC1A2SLC1A1MAPTCA2 | |
| SCHEMBL5858256 | 0.81 | ALDH1A1 (0.36) | SLC1A3SLC1A2SLC1A1MAPTCA2 | |
| SCHEMBL19255396 | 0.74 | CYP2C19 (0.30) | — | |
| SCHEMBL4879424 | 0.73 | CA2 (0.39) | SLC1A3SLC1A2SLC1A1MAPTCA2 | |
| SCHEMBL1771911 | 0.73 | MAPT (0.33) | SLC1A3SLC1A2SLC1A1MAPTCA2 | |
| SCHEMBL993239 | 0.71 | CHRM1 (0.33) | SLC1A3SLC1A2SLC1A1MAPTCA2 | |
| SCHEMBL6698477 | 0.71 | TP53 (0.35) | — | |
| Ethylmalonate SCHEMBL107241 | 0.71 | — | — | |
| SCHEMBL16957999 | 0.70 | FAAH (0.32) | SLC1A3SLC1A2SLC1A1MAPTCA2 | |
| SCHEMBL17433678 | 0.70 | CA2 (0.37) | SLC1A3SLC1A2SLC1A1MAPTCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595962-B1 | PROCESS FOR THE PREPARATION OF ESTERS OF 1-SUBSTITUTED-3-FLUOROALKYL-PYRAZOLE-4-CARBOXYLIC ACIDS | SOLVAY (BE) | 2018-07-11 | — | — | EP | disclosed |
| EP-2809653-B1 | METHOD FOR PRODUCING 3,5-BIS(FLUORALKYL)-PYRAZOL-4-CARBOXYLIC ACID DERIVATIVES AND 3,5-BIS(FLUORALKYL)-PYRAZOLES | BAYER CROPSCIENCE AG (DE) | 2017-08-16 | — | — | EP | disclosed |
| EP-2671874-B1 | Preparation of esters of 1-substituted-3-fluoroalkyl-pyrazole-4-carboxylic acids | SOLVAY (BE) | 2016-01-13 | — | — | EP | disclosed |
| US-8981116-B2 | Process for the preparation of esters of 1-substituted-3-fluoroalkyl-pyrazole-4-carboxylic acids | SOLVAY SA (BE) | 2015-03-17 | — | — | US | disclosed |
| EP-2809653-A1 | METHOD FOR PRODUCING 3,5-BIS(FLUOROALKYL)-PYRAZOL-4-CARBOXYLIC ACID DERIVATIVES AND 3,5-BIS(FLUOROALKYL)-PYRAZOLES | Bayer CropScience AG (DE) | 2014-12-10 | — | — | EP | disclosed |
| EP-2671874-A1 | Preparation of esters of 1-substituted-3-fluoroalkyl-pyrazole-4-carboxylic acids | SOLVAY SA (BE) | 2013-12-11 | — | — | EP | disclosed |
| WO-2013113829-A1 | METHOD FOR PRODUCING 3,5-BIS(FLUOROALKYL)-PYRAZOL-4-CARBOXYLIC ACID DERIVATIVES AND 3,5-BIS(FLUOROALKYL)-PYRAZOLES | BAYER CROPSCIENCE AG (DE) | 2013-08-08 | — | — | WO | disclosed |
| EP-2623496-A1 | Method for producing 3,5-bis(fluoralkyl)-pyrazol-4-carboxylic acid derivatives and 3,5-bis(fluoralkyl)-pyrazoles | Bayer CropScience AG (DE) | 2013-08-07 | — | — | EP | disclosed |
| EP-2595962-A1 | PROCESS FOR THE PREPARATION OF ESTERS OF 1-SUBSTITUTED-3-FLUOROALKYL-PYRAZOLE-4-CARBOXYLIC ACIDS | SOLVAY SA (BE) | 2013-05-29 | — | — | EP | disclosed |
| US-20130123510-A1 | Process for the preparation of esters of 1-substituted-3-fluoroalkyl-pyrazole-4-carboxylic acids | SOLVAY SA (BE) | 2013-05-16 | — | — | US | disclosed |
| WO-2012025469-A1 | IMPROVED PROCESS FOR THE PREPARATION OF ESTERS OF 1-H-PYRAZOLE-4-CARBOXYLIC ACIDS | SOLVAY SA (BE) | 2012-03-01 | — | — | WO | disclosed |
| WO-2012010692-A1 | PROCESS FOR THE PREPARATION OF ESTERS OF 1-SUBSTITUTED-3-FLUOROALKYL-PYRAZOLE-4-CARBOXYLIC ACIDS | SOLVAY SA (BE) | 2012-01-26 | — | — | WO | disclosed |
| EP-2398759-A2 | COMPOSITIONS OF ESTERS OF FLUOROSUBSTITUTED ALCANOIC ACIDS | Solvay Fluor GmbH (DE) | 2011-12-28 | — | — | EP | disclosed |
| US-20110297883-A1 | Compositions of esters of fluorosubstituted alcanoic acids | SOLVAY FLUOR GMBH (DE) | 2011-12-08 | — | — | US | disclosed |
| WO-2010094746-A2 | COMPOSITIONS OF ESTERS OF FLUOROSUBSTITUTED ALCANOIC ACIDS | SOLVAY FLUOR GMBH (DE) | 2010-08-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123510-A1 | Process for the preparation of esters of 1-substituted-3-fluoroalkyl-pyrazole-4-carboxylic acids | CYP2F1, KHK, CYP4F3 | SLC1A3 2569/4885SLC1A2 2981/4885SLC1A1 2774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.