Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.32 |
| ▸ | AKT1 | P31749 | 2/20 | 0.32 |
| ▸ | AKT2 | P31751 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16594044 | 0.85 | POLB (0.46) | — | |
| SCHEMBL15412773 | 0.83 | BRD4 (0.40) | BRD4PDE10AAKT1AKT2 | |
| SCHEMBL16803686 | 0.81 | PDE10A (0.38) | BRD4PDE10AAKT1AKT2 | |
| SCHEMBL10249250 | 0.81 | PDE10A (0.38) | BRD4PDE10AAKT1AKT2 | |
| SCHEMBL16604838 | 0.81 | BRD4 (0.35) | BRD4PDE10AAKT1AKT2 | |
| SCHEMBL16604829 | 0.81 | AKT1 (0.34) | BRD4PDE10AAKT1AKT2 | |
| SCHEMBL15426455 | 0.80 | LMNA (0.34) | BRD4PDE10AAKT1AKT2 | |
| SCHEMBL15426390 | 0.80 | TNKS (0.38) | BRD4PDE10A | |
| SCHEMBL15426384 | 0.80 | RORC (0.37) | BRD4PDE10AAKT1AKT2 | |
| SCHEMBL16604825 | 0.80 | BRD4 (0.35) | BRD4PDE10AAKT1AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9120792-B2 | Fused heterocyclic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-09-01 | — | — | US | disclosed |
| US-20150094329-A1 | FUSED HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150094329-A1 | FUSED HETEROCYCLIC COMPOUND | CYC1, H1-0, H1-3 | BRD4 1812/4885PDE10A 3851/4885AKT1 444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.