SCHEMBL1660690

SCHEMBL1660690

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nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MPI P34949 1/20 0.43
AKR1B1 P15121 1/20 0.42
LMNA P02545 2/20 0.38
ALDH1A1 P00352 1/20 0.38
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17984942 1.00 MPI (0.43) MPIAKR1B1LMNAALDH1A1THRB
SCHEMBL4167823 1.00 MPI (0.43) MPIAKR1B1LMNAALDH1A1THRB
SCHEMBL450548 1.00 MPI (0.43) MPIAKR1B1LMNAALDH1A1THRB
Phosphoric Acid SCHEMBL5789226 0.93 MPI (0.48) MPIAKR1B1LMNAALDH1A1
SCHEMBL15855477 0.86 AKR1B1 (0.39) MPIAKR1B1LMNAALDH1A1
Glycerin SCHEMBL9110886 0.82 LMNA (0.47) MPIAKR1B1LMNAALDH1A1THRB
SCHEMBL17984949 0.81 THRB (0.40) MPIAKR1B1THRB
SCHEMBL17984951 0.80 AKR1B1 (0.42) MPIAKR1B1LMNA
SCHEMBL19859338 0.79 MPI (0.34) MPILMNA
SCHEMBL42624 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110183926-A1 TREATMENT USING CONTINUOUS LOW DOSE APPLICATION OF SUGAR ANALOGS UNIVERSITY OF MIAMI (US) 2011-07-28 US claimed
EP-2303282-A2 TREATMENT USING CONTINUOUS LOW DOSE APPLICATION OF SUGAR ANALOGS University of Miami (US) 2011-04-06 EP claimed
WO-2009143515-A2 TREATMENT USING CONTINUOUS LOW DOSE APPLICATION OF SUGAR ANALOGS UNIVERSITY OF MIAMI (US) 2009-11-26 WO claimed
EP-0582153-B1 Method of preparing 4-deoxy-D-mannose JAPAN TOBACCO INC (JP) 1996-01-17 EP claimed
EP-0582153-A1 Method of preparing 4-deoxy-D-mannose Japan Tobacco Inc. (JP) 1994-02-09 EP claimed
US-20230242585-A1 IMMUNOMODULATORS BRISTOL MYERS SQUIBB CO (US) 2023-08-03 US disclosed
US-10793590-B2 Antifungal compounds PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2020-10-06 US disclosed
US-20190211047-A1 ANTIFUNGAL COMPOUNDS PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2019-07-11 US disclosed
US-9994603-B2 Epimerisation of saccharides CARGILL, INCORPORATED (US) 2018-06-12 US disclosed
WO-2017210565-A1 ANTIFUNGAL COMPOUNDS PRISIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2017-12-07 WO disclosed
CN-106520864-A Method for enzymatic synthesis of sialic acid analogue and application thereof 南京农业大学 2017-03-22 CN disclosed
CN-102883804-B The epimerization of sugar 卡吉尔公司 2016-10-12 CN disclosed
EP-0710501-A2 Catalyst regeneration CERESTAR HOLDING BV (NL) 1996-05-08 EP disclosed
EP-0582153-B1 Method of preparing 4-deoxy-D-mannose JAPAN TOBACCO INC (JP) 1996-01-17 EP disclosed
EP-0582153-B1 Method of preparing 4-deoxy-D-mannose JAPAN TOBACCO INC (JP) 1996-01-17 EP disclosed
EP-0582153-A1 Method of preparing 4-deoxy-D-mannose Japan Tobacco Inc. (JP) 1994-02-09 EP disclosed
EP-0582153-A1 Method of preparing 4-deoxy-D-mannose Japan Tobacco Inc. (JP) 1994-02-09 EP disclosed
EP-0582153-A1 Method of preparing 4-deoxy-D-mannose Japan Tobacco Inc. (JP) 1994-02-09 EP disclosed
EP-0400064-B1 SOLID CATALYSTS FOR CONTINUOUS INTERCONVERSION OF EPIMERIC ALDOSES AND ALDOSE ANALOGS UOP (US) 1993-04-21 EP disclosed
US-4815445-A ANION EXCHANGE RESIN ALLIED-SIGNAL INC. (US) 1989-03-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242585-A1 IMMUNOMODULATORS CD274, PDCD1, PDCD1LG2 MPI 1619/4885AKR1B1 4582/4885LMNA 4649/4885
US-10793590-B2 Antifungal compounds DPM1, NACA, SUCLG1 MPI 725/4885AKR1B1 531/4885LMNA 1413/4885
US-20190211047-A1 ANTIFUNGAL COMPOUNDS DPM1, NACA, SUCLG1 MPI 725/4885AKR1B1 531/4885LMNA 1413/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.