SCHEMBL1660706

SCHEMBL1660706

Nc1ccc(C(F)(C(F)F)C(F)(F)F)c(O)c1N

nearest known ligand 0.32

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.32
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GLA P06280 1/20 0.30
POLB P06746 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
KMT2A Q03164 1/20 0.30
ATM Q13315 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21835030 0.79 SMN1; SMN2 (0.30) SMN1; SMN2
SCHEMBL28414798 0.79 MMP2 (0.35)
SCHEMBL17580759 0.79
SCHEMBL28443534 0.75 CA12 (0.38) SMN1; SMN2
SCHEMBL1660718 0.74 CD44 (0.34) ALDH1A1HPGDHSD17B10
SCHEMBL21835028 0.72 MEN1 (0.30) MEN1ALDH1A1POLBMAPTKMT2A
SCHEMBL9687748 0.72 MEN1 (0.38) MEN1ALDH1A1KMT2A
SCHEMBL28844879 0.71 TSHR (0.38) KDM4EMEN1ALDH1A1GLAPOLB
SCHEMBL28217056 0.71 G6PD (0.35) SMN1; SMN2KDM4EMEN1ALDH1A1GLA
SCHEMBL2024257 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2861650-B1 POLYIMIDE RESIN AND POLYIMIDE FILM PRODUCED THEREFROM KOLON INC (KR) 2019-03-20 EP claimed
US-20160096952-A1 POLYIMIDE RESIN AND POLYIMIDE FILM PRODUCED THEREFROM KOLON INDUSTRIES, INC. (KR) 2016-04-07 US claimed
EP-2861650-A1 POLYIMIDE RESIN AND POLYIMIDE FILM PRODUCED THEREFROM Kolon Industries, Inc. (KR) 2015-04-22 EP claimed
CN-113260676-B Polyimide film having excellent weather resistance 株式会社斗山 2025-02-07 CN disclosed
CN-113260675-B Polyimide film having excellent yield strain and bending characteristics 株式会社斗山 2024-06-07 CN disclosed
WO-2021117961-A1 POLYIMIDE FILM HAVING EXCELLENT WEATHER RESISTANCE 주식회사 두산 2021-06-17 WO disclosed
WO-2021117960-A1 POLYIMIDE FILM HAVING EXCELLENT YIELD STRAIN AND FLEXURAL CHARACTERISTICS 주식회사 두산 2021-06-17 WO disclosed
EP-2861650-B1 POLYIMIDE RESIN AND POLYIMIDE FILM PRODUCED THEREFROM KOLON INC (KR) 2019-03-20 EP disclosed
CN-104379636-B Polyimide resin and polyimide film produced from the same 可隆工业株式会社 2018-04-17 CN disclosed
US-20160096952-A1 POLYIMIDE RESIN AND POLYIMIDE FILM PRODUCED THEREFROM KOLON INDUSTRIES, INC. (KR) 2016-04-07 US disclosed
EP-2861650-A1 POLYIMIDE RESIN AND POLYIMIDE FILM PRODUCED THEREFROM Kolon Industries, Inc. (KR) 2015-04-22 EP disclosed
CN-104379636-A Polyimide resin and polyimide film produced from the same KOLON INC 2015-02-25 CN disclosed
US-20110082276-A1 TRANSPARENT POLYIMIDE FILM HAVING IMPROVED SOLVENT RESISTANCE KOLON INDUSTRIES, INC. (KR) 2011-04-07 US disclosed