Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11903895 | 0.81 | CRHR1 (0.46) | CRHR1ERG | |
| SCHEMBL1660702 | 0.79 | CRHR1 (0.39) | CRHR1ERG | |
| SCHEMBL1613880 | 0.79 | CRHR1 (0.52) | CRHR1 | |
| SCHEMBL1661744 | 0.78 | CRHR1 (0.59) | CRHR1ERG | |
| SCHEMBL12731365 | 0.78 | CRHR1 (0.42) | CRHR1ERG | |
| SCHEMBL1661735 | 0.78 | CRHR1 (0.41) | CRHR1ERG | |
| SCHEMBL1660703 | 0.76 | CRHR1 (0.38) | CRHR1ERG | |
| SCHEMBL1662891 | 0.75 | CRHR1 (0.66) | CRHR1ERG | |
| SCHEMBL11920839 | 0.74 | CRHR1 (0.51) | CRHR1ERG | |
| SCHEMBL12790133 | 0.74 | CRHR1 (0.38) | CRHR1ERG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086898-A1 | PYRAZOLOOXAZOLE COMPOUND | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086898-A1 | PYRAZOLOOXAZOLE COMPOUND | CRHR1, MC2R, CRHR2 | CRHR1 1/4885ERG 1544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.