Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17679906 | 0.85 | OPRM1 (0.46) | OPRM1OPRD1OPRK1OPRL1GRIN2B | |
| SCHEMBL29060516 | 0.74 | OPRM1 (0.59) | OPRM1OPRD1OPRK1OPRL1GRIN2B | |
| SCHEMBL2270935 | 0.74 | SIGMAR1 (0.62) | OPRM1OPRD1OPRK1OPRL1GRIN2B | |
| Hydrochloric Acid SCHEMBL8175707 | 0.73 | SIGMAR1 (0.60) | OPRM1OPRD1OPRK1OPRL1GRIN2B | |
| SCHEMBL8959891 | 0.72 | HTR2A (0.45) | OPRM1OPRD1OPRK1OPRL1GRIN2B | |
| SCHEMBL27625085 | 0.71 | OPRM1 (0.56) | OPRM1OPRD1OPRK1OPRL1GRIN2B | |
| SCHEMBL29273456 | 0.71 | OPRM1 (0.47) | OPRM1OPRD1OPRK1OPRL1GRIN2B | |
| SCHEMBL28994161 | 0.71 | OPRM1 (0.56) | OPRM1OPRD1OPRK1OPRL1GRIN2B | |
| Tert-Butyl Formate SCHEMBL27827350 | 0.70 | TDP1 (0.37) | OPRM1OPRD1OPRK1OPRL1GRIN2B | |
| SCHEMBL16600702 | 0.70 | GRIN2B (0.52) | OPRM1OPRD1OPRK1OPRL1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015048507-A1 | SELECTIVE OCTAHYDRO-CYCLOPENTA[C] PYRROLE NEGATIVE MODULATORS OF NR2B | MNEMOSYNE PHARMACEUTICALS, INC. (US) | 2015-04-02 | — | — | WO | disclosed |