Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.36 |
| ▸ | MAOB | P27338 | 7/20 | 0.36 |
| ▸ | KDM1A | O60341 | 5/20 | 0.36 |
| ▸ | BPTF | Q12830 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18373227 | 1.00 | MAOA (0.36) | MAOAMAOBKDM1ABPTFMC4R | |
| SCHEMBL16601300 | 0.78 | GRIN2B (0.46) | MAOAMAOBKDM1ABPTFMC4R | |
| SCHEMBL16608272 | 0.78 | GRIN2B (0.46) | MAOAMAOBKDM1ABPTFMC4R | |
| SCHEMBL16995950 | 0.78 | GRIN2B (0.46) | MAOAMAOBKDM1ABPTFMC4R | |
| SCHEMBL16601297 | 0.78 | GRIN2B (0.46) | MAOAMAOBKDM1ABPTFMC4R | |
| SCHEMBL16608218 | 0.77 | LMNA (0.42) | MAOAMAOBKDM1ABPTFMC4R | |
| SCHEMBL13451156 | 0.75 | MAOA (0.37) | MAOAMAOBKDM1ARCOR1GRIN2B | |
| SCHEMBL23805616 | 0.71 | GRIN2B (0.50) | GRIN2B | |
| SCHEMBL16600819 | 0.71 | GRIN2B (0.50) | GRIN2B | |
| SCHEMBL16600821 | 0.71 | GRIN2B (0.50) | GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015048507-A1 | SELECTIVE OCTAHYDRO-CYCLOPENTA[C] PYRROLE NEGATIVE MODULATORS OF NR2B | MNEMOSYNE PHARMACEUTICALS, INC. (US) | 2015-04-02 | — | — | WO | disclosed |