Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.42 |
| ▸ | ACHE | P22303 | 5/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1660381 | 0.86 | NLRP3 (0.34) | BCHEACHENLRP3 | |
| SCHEMBL2871922 | 0.80 | P2RX3 (0.45) | — | |
| SCHEMBL4237483 | 0.80 | NLRP3 (0.39) | NLRP3 | |
| SCHEMBL12563371 | 0.79 | PDE2A (0.42) | BCHEACHENLRP3 | |
| SCHEMBL1660196 | 0.79 | PTGS1 (0.45) | — | |
| SCHEMBL12604716 | 0.78 | PDE2A (0.41) | BCHEACHENLRP3 | |
| SCHEMBL4236233 | 0.76 | GNRHR (0.36) | BCHEACHENLRP3 | |
| SCHEMBL2638909 | 0.75 | P2RX3 (0.40) | — | |
| SCHEMBL4242022 | 0.74 | GNRHR (0.37) | BCHEACHENLRP3 | |
| SCHEMBL13743202 | 0.74 | BCHE (0.41) | BCHEACHENLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307394-B1 | SULPHONAMIDES AS VANILLOID RECEPTOR ANTAGONIST | AMOREPACIFIC CORP (KR) | 2012-09-26 | — | — | EP | disclosed |
| EP-2307394-A2 | NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Amorepacific Corporation (KR) | 2011-04-13 | — | — | EP | disclosed |
| WO-2010002209-A2 | NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | AMOREPACIFIC CORPORATION (KR) | 2010-01-07 | — | — | WO | disclosed |