Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL7072609 | 0.90 | ALDH1A1 (0.33) | ALDH1A1MAPTHPGDRECQL | |
| SCHEMBL6154105 | 0.87 | ALDH1A1 (0.40) | ALDH1A1KEAP1NFE2L2HCAR2MAPT | |
| SCHEMBL6154107 | 0.87 | ALDH1A1 (0.40) | ALDH1A1KEAP1NFE2L2HCAR2MAPT | |
| SCHEMBL166921 | 0.87 | ALDH1A1 (0.40) | ALDH1A1KEAP1NFE2L2HCAR2MAPT | |
| SCHEMBL23394794 | 0.84 | NPSR1 (0.50) | ALDH1A1MAPTNPSR1 | |
| SCHEMBL7172761 | 0.81 | MAPT (0.32) | ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL7171266 | 0.81 | MAPT (0.32) | ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL11656078 | 0.81 | ALDH1A1 (0.31) | ALDH1A1MAPTHPGDRECQL | |
| SCHEMBL7173968 | 0.81 | MAPT (0.32) | ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL17164534 | 0.79 | ALDH1A1 (0.30) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 471 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118604214-A | Method for analyzing amine metabolites in soil by DMMMM derivatization-liquid chromatography | 贵州省烟草科学研究院 | 2024-09-06 | — | — | CN | claimed |
| CN-113480477-A | Preparation process of 4-trifluoromethyl nicotinic acid | 江西汇和化工有限公司 | 2021-10-08 | — | — | CN | claimed |
| CN-107298653-A | A kind of method for synthesizing 4 trifluoromethyl nicotinic acids | 江苏建农植物保护有限公司 | 2017-10-27 | — | — | CN | claimed |
| US-4851566-A | CONDENSING ALKYL MALONATE WITH ORTHOESTER IN PRESENCE OF CARBOXYLIC ACID AND CADMIUM OR MAGNESIUM COMPOUND CATALYST | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1989-07-25 | — | — | US | claimed |
| EP-0152319-B1 | PROCESS FOR OBTAINING COMPOUNDS WITH AN ALKOXYACYLIDENE GROUP | RHONE-POULENC CHIMIE (FR) | 1987-07-22 | — | — | EP | claimed |
| JP-1228974-A | — | — | None | — | — | JP | disclosed |
| US-20250270210-A1 | BCL-2 Inhibitor | BEIGENE, LTD. (KY) | 2025-08-28 | — | — | US | disclosed |
| EP-4004000-B1 | THIENOPYRIDINYL AND THIAZOLOPYRIDINYL COMPOUNDS USEFUL AS IRAK4 INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2025-07-09 | — | — | EP | disclosed |
| US-12304916-B2 | Thienopyridinyl and thiazolopyridinyl compounds useful as IRAK4 inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-05-20 | — | — | US | disclosed |
| US-12286430-B2 | Bcl-2 inhibitor | BEIGENE, LTD. (KY) | 2025-04-29 | — | — | US | disclosed |
| CN-119735546-A | Preparation method of 4-trifluoromethyl nicotinic acid | 帕潘纳(北京)科技有限公司 | 2025-04-01 | — | — | CN | disclosed |
| WO-2025008288-A1 | 9-OXO-9,10-DIHYDRO-6H-PYRANO[3,2-B:4,5-B']DIPYRIDINE-8-CARBOXYLIC ACID DERIVATIVES | CENTENARA LABS AG (CH) | 2025-01-09 | — | — | WO | disclosed |
| US-4104049-A | Chlorine-substituted vinylaminobenzoic acid compounds and plant growth regulant compositions | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-01 | — | — | US | disclosed |
| US-4086233-A | ANTIALLERGENS | STERLING DRUG INC. (US) | 1978-04-25 | — | — | US | disclosed |
| US-4072679-A | CNS DEPRESSANTS, ANTIINFLAMMATORY AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1978-02-07 | — | — | US | disclosed |
| US-4072746-A | CARDIOTONIC AGENTS | STERLING DRUG INC. (US) | 1978-02-07 | — | — | US | disclosed |
| US-4058553-A | Method of preparing alkoxymethylenemalonic acid esters | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) | 1977-11-15 | — | — | US | disclosed |
| US-4032523-A | ANTIALLERGENS | STERLING DRUG INC. (US) | 1977-06-28 | — | — | US | disclosed |
| US-4018770-A | ANTIALLERGENS | STERLING DRUG INC. (US) | 1977-04-19 | — | — | US | disclosed |
| US-3992380-A | 5,8-Dihydro-5-oxo-2-(4-or 3-pyridinyl)pyrido[2,3-d]pyrimidine-6-carboxylic acids and esters | STERLING DRUG INC. (US) | 1976-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250270210-A1 | BCL-2 Inhibitor | BCL2, BCL2A1, BCL2L1 | ALDH1A1 2918/4885KEAP1 1412/4885NFE2L2 236/4885 |
| US-12304916-B2 | Thienopyridinyl and thiazolopyridinyl compounds useful as IRAK4 inhibitors | IRAK4, IRAK1, IRAK2 | ALDH1A1 2699/4885KEAP1 1839/4885NFE2L2 3219/4885 |
| US-12286430-B2 | Bcl-2 inhibitor | BCL2, BCL2A1, BCL2L1 | ALDH1A1 2918/4885KEAP1 1412/4885NFE2L2 236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.