SCHEMBL16610032

SCHEMBL16610032

CC1(c2cc(Br)c(Br)s2)OCCO1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HCAR3 P49019 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25416440 0.82
SCHEMBL16610034 0.81 CYP11B1 (0.31)
SCHEMBL1167218 0.69 BACE1 (0.41) HCAR3HCAR2
SCHEMBL855647 0.68
SCHEMBL16610037 0.68 CYP11B1 (0.38)
SCHEMBL22870152 0.65 BACE1 (0.30)
SCHEMBL21963195 0.65 CYP11B1 (0.33)
SCHEMBL22870328 0.64 BACE1 (0.37)
SCHEMBL11859145 0.64 LMNA (0.43)
SCHEMBL6493827 0.64 TSHR (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015043364-A1 BENZOXAZOLEOXAZINE KETONE COMPOUND AS BLOOD COAGULATION FACTOR XA INHIBITOR 华北制药集团新药研究开发有限责任公司 2015-04-02 WO disclosed