Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16610037 | 0.81 | CYP11B1 (0.38) | CYP11B1CYP11B2MEN1LMNAPABPC1 | |
| SCHEMBL16610032 | 0.81 | HCAR3 (0.32) | — | |
| SCHEMBL21963195 | 0.73 | CYP11B1 (0.33) | CYP11B1CYP11B2 | |
| SCHEMBL25416440 | 0.72 | — | — | |
| SCHEMBL22870328 | 0.69 | BACE1 (0.37) | CYP11B1CYP11B2 | |
| SCHEMBL1167218 | 0.67 | BACE1 (0.41) | — | |
| SCHEMBL22019972 | 0.66 | CYP11B1 (0.33) | CYP11B1CYP11B2 | |
| SCHEMBL5635402 | 0.66 | KMT2A (0.41) | MEN1LMNAPABPC1KMT2ASMN1; SMN2 | |
| SCHEMBL5276807 | 0.66 | SMN1; SMN2 (0.43) | CYP11B1CYP11B2MEN1LMNAPABPC1 | |
| SCHEMBL21963419 | 0.65 | SMN1; SMN2 (0.34) | MEN1LMNAPABPC1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015043364-A1 | BENZOXAZOLEOXAZINE KETONE COMPOUND AS BLOOD COAGULATION FACTOR XA INHIBITOR | 华北制药集团新药研究开发有限责任公司 | 2015-04-02 | — | — | WO | disclosed |