SCHEMBL21362263

SCHEMBL21362263

Cn1cc(Cn2cc(C(=O)NC3CCCCC3)c3c(F)ccc(F)c32)cn1

nearest known ligand 0.60

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 13/20 0.60
CNR1 P21554 4/20 0.47
CNR2 P34972 4/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18645652 0.88 CHRM1 (0.77) CHRM1
SCHEMBL18644822 0.87 CHRM1 (0.79) CHRM1CNR1CNR2
SCHEMBL16610091 0.84 CNR1 (0.49) CHRM1CNR1CNR2
SCHEMBL21362279 0.82 CHRM1 (0.78) CHRM1CNR1CNR2
SCHEMBL20481676 0.81 CHRM1 (0.76) CHRM1
SCHEMBL16597530 0.81 CHRM1 (0.51) CHRM1
SCHEMBL18644829 0.81 CHRM1 (0.76) CHRM1
SCHEMBL21362277 0.80 CHRM1 (0.79) CHRM1
Hydrochloric Acid SCHEMBL20481666 0.80 CHRM1 (0.75) CHRM1
Hydrochloric Acid SCHEMBL18614784 0.80 CHRM1 (0.75) CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3347349-B1 FLUOROINDOLE DERIVATIVES AS MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS SUVEN LIFE SCIENCES LTD (IN) 2019-09-18 EP disclosed