SCHEMBL16610346

SCHEMBL16610346

Cc1ccc(Cc2ccc(S(=O)(=O)c3ccc(Oc4ccc(S(C)(=O)=O)cc4)cc3)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
TDP1 Q9NUW8 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
GAA P10253 1/20 0.50
BCHE P06276 2/20 0.46
ACHE P22303 2/20 0.46
PTGS2 P35354 4/20 0.45
PTGS1 P23219 3/20 0.44
NR3C1 P04150 1/20 0.43
FFAR1 O14842 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
PKM P14618 1/20 0.42
S1PR1 P21453 1/20 0.41
S1PR3 Q99500 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13155652 1.00 HTT (0.61) HTTSMN1; SMN2TDP1L3MBTL1GAA
SCHEMBL19341781 0.95 HTT (0.53) HTTSMN1; SMN2TDP1L3MBTL1BCHE
SCHEMBL822854 0.94 HTT (0.69) HTTSMN1; SMN2TDP1L3MBTL1GAA
SCHEMBL13321724 0.94 HTT (0.69) HTTSMN1; SMN2TDP1L3MBTL1GAA
SCHEMBL23153426 0.90 HTT (0.73) HTTSMN1; SMN2TDP1L3MBTL1GAA
SCHEMBL19105488 0.90 HTT (0.73) HTTSMN1; SMN2TDP1L3MBTL1GAA
SCHEMBL10016733 0.90 HTT (0.73) HTTSMN1; SMN2TDP1L3MBTL1GAA
SCHEMBL822952 0.89 HTT (0.63) HTTSMN1; SMN2TDP1L3MBTL1GAA
SCHEMBL12769576 0.89 HTT (0.63) HTTSMN1; SMN2TDP1L3MBTL1GAA
SCHEMBL13291969 0.88 HTT (0.61) HTTSMN1; SMN2TDP1L3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150093562-A1 Conductive Thermoplastic Resin Composition LOTTE ADVANCED MATERIALS CO., LTD. (KR) 2015-04-02 US disclosed