SCHEMBL19105488

SCHEMBL19105488

Cc1ccc(Oc2ccc(S(=O)(=O)c3ccc(Oc4ccc(S(C)(=O)=O)cc4)cc3)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTT P42858 5/20 0.73
SMN1; SMN2 Q16637 3/20 0.73
TDP1 Q9NUW8 1/20 0.65
L3MBTL1 Q9Y468 1/20 0.65
GAA P10253 1/20 0.61
PTGS2 P35354 6/20 0.51
PTGS1 P23219 2/20 0.50
PKM P14618 1/20 0.50
FFAR1 O14842 1/20 0.49
ALDH1A1 P00352 3/20 0.47
MEN1 O00255 1/20 0.47
MAPT P10636 1/20 0.47
KMT2A Q03164 1/20 0.47
LMNA P02545 2/20 0.46
TEAD4 Q15561 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10016733 1.00 HTT (0.73) HTTSMN1; SMN2TDP1L3MBTL1GAA
SCHEMBL23153426 1.00 HTT (0.73) HTTSMN1; SMN2TDP1L3MBTL1GAA
SCHEMBL9888806 0.95 HTT (0.67) HTTSMN1; SMN2TDP1L3MBTL1GAA
SCHEMBL15097133 0.95 HTT (0.67) HTTSMN1; SMN2TDP1L3MBTL1GAA
SCHEMBL10014119 0.95 HTT (0.67) HTTSMN1; SMN2TDP1L3MBTL1GAA
SCHEMBL2758531 0.94 HTT (0.63) HTTSMN1; SMN2TDP1L3MBTL1GAA
SCHEMBL13814624 0.94 HTT (0.63) HTTSMN1; SMN2TDP1L3MBTL1GAA
SCHEMBL10084171 0.92 HTT (0.85) HTTSMN1; SMN2TDP1L3MBTL1GAA
SCHEMBL2606163 0.92 HTT (0.85) HTTSMN1; SMN2TDP1L3MBTL1GAA
SCHEMBL12268296 0.92 HTT (0.85) HTTSMN1; SMN2TDP1L3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230321610-A1 HOLLOW FIBER MEMBRANE FOR SEPARATING BLOOD PLASMA FROM BLOOD FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH (DE) 2023-10-12 US disclosed
US-20170200919-A1 SOLUTION-PROCESSABLE HRI OPTICAL FILMS COMPRISING TITANATE NANOPARTICLES AVANTAMA AG (CH) 2017-07-13 US disclosed