Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23153426 | 1.00 | HTT (0.73) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL19105488 | 1.00 | HTT (0.73) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL10014119 | 0.95 | HTT (0.67) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL9888806 | 0.95 | HTT (0.67) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL15097133 | 0.95 | HTT (0.67) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL13814624 | 0.94 | HTT (0.63) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL2758531 | 0.94 | HTT (0.63) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL822843 | 0.92 | HTT (0.85) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL2606163 | 0.92 | HTT (0.85) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL12268296 | 0.92 | HTT (0.85) | HTTSMN1; SMN2TDP1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165467-A1 | NEW POLYELECTROLYTE COMPLEXES AND THE USE THEREOF | HERAEUS PRECIOUS METALS GMBH & CO. KG | 2012-06-28 | — | — | US | disclosed |