SCHEMBL728026

SCHEMBL728026

CO[Si](CNC(N)=O)(OC)OC

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36
TDP1 Q9NUW8 1/20 0.33
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.31
MTNR1A P48039 1/20 0.30
MTNR1B P49286 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL728593 0.86 TDP1 (0.32) TSHRTDP1
SCHEMBL728336 0.86 ALOX15 (0.32) TSHR
SCHEMBL133714 0.79 MTNR1A (0.39) TSHRTDP1MTNR1AMTNR1B
SCHEMBL2107299 0.79 TSHR (0.40) TSHRTDP1KDM4ELMNA
SCHEMBL2460035 0.79 TSHR (0.35) TSHRTDP1KDM4ELMNA
SCHEMBL16610541 0.78 CYP2D6 (0.37) TSHR
SCHEMBL141335 0.78 EPHX1 (0.40) TSHR
SCHEMBL13317345 0.78 KDM4E (0.39) TSHRKDM4EMTNR1AMTNR1B
SCHEMBL729764 0.77 ALOX15 (0.36) TDP1
SCHEMBL14027917 0.76 TSHR (0.31) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 237 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140097392-A1 LIQUID COATING COMPOSITIONS OF POLYMER MATRIX RESINS WITH PHOTOCHROMIC DYES AND FILMS MADE THEREFROM E I DU PONT DE NEMOURS AND COMPANY (US) 2014-04-10 US claimed
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP claimed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US claimed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US claimed
US-12601970-B2 Photosensitive resin composition, method for manufacturing patterned cured product, cured product, interlayer insulating film, cover coat layer, surface protective film, and electronic component HD MICROSYSTEMS, LTD. (JP) 2026-04-14 US disclosed
EP-4698580-A1 CROSSLINKABLE COMPOSITIONS BASED ON SILANE-CROSSLINKING ORGANIC POLYMERS WITH HIGH THERMAL CONDUCTIVITY Wacker Chemie AG (DE) 2026-02-25 EP disclosed
EP-4665796-A1 CURABLE POLYSILOXANE COMPOSITION AND ENCAPSULANT INCLUDING THE SAME Wacker Chemie AG (DE) 2025-12-24 EP disclosed
US-20250362601-A1 Photosensitive Resin Composition, Method Of Manufacturing Pattern Cured Film, Cured Film, Interlayer Insulating Film, Cover Coat Layer, Surface Protective Film, And Electronic Component HD MICROSYSTEMS LTD (JP) 2025-11-27 US disclosed
US-12466910-B2 Rubber composition and tire TOYO TIRE CORPORATION (JP) 2025-11-11 US disclosed
EP-4496825-B1 A COMPOSITION WACKER CHEMIE AG (DE) 2025-10-15 EP disclosed
US-12441824-B2 2025-10-14 US disclosed
US-12392693-B2 Hydrophilic substrate and method for preparing hydrophilic substrate SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2025-08-19 US disclosed
US-20080023138-A1 Process for Transferring onto a Surface of an Optical Article a Coating Stack Imparting Antistatic Properties ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE 2008-01-31 US disclosed
EP-1388607-B1 Dyeing method of plastic lens and dyeing device NIDEK KK (JP) 2007-12-12 EP disclosed
WO-2007068760-A2 ARTICLE COATED WITH A ULTRA HIGH HYDROPHOBIC FILM AND PROCESS FOR OBTAINING SAME ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) 2007-06-21 WO disclosed
US-20070141114-A1 Article coated with an ultra high hydrophobic film and process for obtaining same ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE 2007-06-21 US disclosed
US-20060075583-A1 Dyeing method of dyeing plastic lens and dyeing device NIDEK CO., LTD. (JP) 2006-04-13 US disclosed
US-7014664-B2 Dyeing method of dyeing plastic lens and dyeing device NIDEK CO., LTD. (JP) 2006-03-21 US disclosed
US-20050071934-A1 Dyeing method of dyeing plastic lens and dyeing device NIDEK CO., LTD. (JP) 2005-04-07 US disclosed
EP-1388607-A2 Dyeing method of plastic lens and dyeing device NIDEK CO., LTD (JP) 2004-02-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12601970-B2 Photosensitive resin composition, method for manufacturing patterned cured product, cured product, interlayer insulating film, cover coat layer, surface protective film, and electronic component ARCN1, P4HA1, COL1A1 TSHR 4385/4885TDP1 2023/4885KDM4E 115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.