Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | CCKAR | P32238 | 2/20 | 0.31 |
| ▸ | CCKBR | P32239 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18054665 | 0.91 | XDH (0.37) | XDH | |
| SCHEMBL16611657 | 0.81 | QPCT (0.32) | FLT3 | |
| SCHEMBL16611549 | 0.80 | BTK (0.31) | — | |
| SCHEMBL16610936 | 0.74 | MARK3 (0.34) | FLT3 | |
| SCHEMBL16611187 | 0.73 | LRRK2 (0.37) | — | |
| SCHEMBL16611559 | 0.72 | QPCT (0.34) | XDH | |
| SCHEMBL16611421 | 0.71 | MEN1 (0.34) | FLT3 | |
| SCHEMBL18052591 | 0.71 | MARK3 (0.32) | FLT3 | |
| SCHEMBL16611298 | 0.71 | OPRM1 (0.31) | FLT3 | |
| SCHEMBL16611259 | 0.71 | BRD4 (0.33) | FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160251352-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2016-09-01 | — | — | US | disclosed |
| US-9371320-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-06-21 | — | — | US | disclosed |
| US-20150141406-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-05-21 | — | — | US | disclosed |
| EP-2857400-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-04-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160251352-A1 | HETEROCYCLIC COMPOUND | JAK2, JAK1, STAT3 | XDH 1789/4885FLT3 1654/4885CCKAR 2222/4885 |
| US-20150141406-A1 | HETEROCYCLIC COMPOUND | JAK2, JAK1, STAT3 | XDH 1789/4885FLT3 1654/4885CCKAR 2222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.