⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28317184 | 0.98 | ALDH1A1 (0.30) | — | |
| SCHEMBL28318228 | 0.98 | ALDH1A1 (0.30) | — | |
| SCHEMBL1942189 | 0.93 | — | — | |
| SCHEMBL1942816 | 0.93 | — | — | |
| SCHEMBL98249 | 0.93 | — | — | |
| SCHEMBL28318141 | 0.83 | ALDH1A1 (0.40) | — | |
| SCHEMBL28318140 | 0.83 | ALDH1A1 (0.40) | — | |
| Tetrahydrofuran SCHEMBL28167504 | 0.83 | ALDH1A1 (0.40) | — | |
| SCHEMBL28318148 | 0.83 | ALDH1A1 (0.40) | — | |
| Tetrahydrofuran-3-Carbaldehyde SCHEMBL67754 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104016959-B | A kind of protosappanin A and its derivatives chemical total synthesis method | 黑龙江大学 | 2017-07-04 | — | — | CN | claimed |
| CN-104016959-A | Biochemical total synthetic method for protosappanin A and derivatives thereof | UNIV HEILONGJIANG | 2014-09-03 | — | — | CN | claimed |
| CN-102731466-A | Diarylo[d,f]oxa-cycloheptane-3-ketone compound and synthesis method thereof | UNIV HEILONGJIANG | 2012-10-17 | — | — | CN | claimed |
| US-20230331724-A1 | PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2023-10-19 | — | — | US | disclosed |
| US-11731971-B2 | Processes for preparing a diazabicyclooctane compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2023-08-22 | — | — | US | disclosed |
| US-20210371419-A1 | PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2021-12-02 | — | — | US | disclosed |
| US-11117896-B2 | Processes for preparing a diazabicyclooctane compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2021-09-14 | — | — | US | disclosed |
| US-20200048253-A1 | PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2020-02-13 | — | — | US | disclosed |
| US-10556905-B2 | Processes for preparing a diazabicyclooctane compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2020-02-11 | — | — | US | disclosed |
| CN-106573927-B | Oxyclohepten-2-yl-pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use | 豪夫迈·罗氏有限公司 | 2019-09-27 | — | — | CN | disclosed |
| EP-2857401-B1 | NOVEL -LACTAMASE INHIBITOR AND METHOD FOR PRODUCING SAME | MEIJI SEIKA PHARMA CO LTD (JP) | 2019-09-18 | — | — | EP | disclosed |
| US-9181250-B2 | Beta-lactamase inhibitor and process for preparing the same | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2015-11-10 | — | — | US | disclosed |
| US-20150141401-A1 | NOVEL BETA-LACTAMASE INHIBITOR AND PROCESS FOR PREPARING THE SAME | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2015-05-21 | — | — | US | disclosed |
| CN-104640858-A | Cyclic ether pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use | HOFFMANN LA ROCHE | 2015-05-20 | — | — | CN | disclosed |
| EP-2857401-A1 | NOVEL -LACTAMASE INHIBITOR AND METHOD FOR PRODUCING SAME | Meiji Seika Pharma Co., Ltd. (JP) | 2015-04-08 | — | — | EP | disclosed |
| CN-104016959-A | Biochemical total synthetic method for protosappanin A and derivatives thereof | UNIV HEILONGJIANG | 2014-09-03 | — | — | CN | disclosed |
| CN-102731466-A | Diarylo[d,f]oxa-cycloheptane-3-ketone compound and synthesis method thereof | UNIV HEILONGJIANG | 2012-10-17 | — | — | CN | disclosed |
| CN-102731466-A | Diarylo[d,f]oxa-cycloheptane-3-ketone compound and synthesis method thereof | UNIV HEILONGJIANG | 2012-10-17 | — | — | CN | disclosed |
| CN-1178922-C | Substituted 1-aminoalkyllactam compounds and their use as muscarinic receptor antagonists | - | 2004-12-08 | — | — | CN | disclosed |
| CN-1430610-A | Substituted 1-aminoalkyllactam compounds and their use as muscarinic receptor antagonists | HOFFMANN LA ROCHE (CH) | 2003-07-16 | — | — | CN | disclosed |