SCHEMBL16612300

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15412786	0.86	POLB (0.43)	POLBPDE10APDE2AKDM4EGRIN1
	SCHEMBL16803698	0.86	AKT1 (0.43)	PDE10AKDM4EALDH1A1MAPTAKT1
	SCHEMBL16612441	0.85	POLB (0.44)	POLBALDH1A1RAB9AGRM2
	SCHEMBL14684622	0.84	POLB (0.42)	POLBPDE10AHDAC1HDAC6HDAC5
	SCHEMBL29431642	0.84	POLB (0.42)	POLBPDE10AHDAC1HDAC6HDAC5
	SCHEMBL15412515	0.83	POLB (0.41)	POLBPDE10APTGS2PDE2AKDM4E
	SCHEMBL116987	0.82	POLB (0.42)	POLBPDE10APTGS2PDE2AGRIN1
	SCHEMBL16611913	0.82	POLB (0.42)	POLBPDE10APTGS2PDE2AGRIN1
	SCHEMBL17824437	0.82	POLB (0.42)	POLBPDE10APTGS2KDM4EALDH1A1
	SCHEMBL16622982	0.82	POLB (0.42)	POLBPDE10APTGS2PDE2AGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.