Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15127767 | 0.73 | ALDH1A1 (0.35) | RAB9AALDH1A1KDM4EKMT2AGAA | |
| SCHEMBL9879740 | 0.72 | RAB9A (0.42) | RAB9AALDH1A1KDM4EKMT2AGAA | |
| SCHEMBL25439588 | 0.70 | RAB9A (0.49) | RAB9AALDH1A1KDM4EKMT2AGAA | |
| SCHEMBL25815768 | 0.69 | MAPT (0.38) | RAB9AALDH1A1KDM4EKMT2AGAA | |
| SCHEMBL6506166 | 0.67 | KDM4E (0.45) | RAB9AALDH1A1KDM4EKMT2AGAA | |
| SCHEMBL2582997 | 0.67 | — | — | |
| SCHEMBL25771601 | 0.67 | RAB9A (0.49) | RAB9AALDH1A1KDM4EKMT2AGAA | |
| SCHEMBL8880070 | 0.66 | — | — | |
| SCHEMBL6585443 | 0.66 | ALDH1A1 (0.37) | ALDH1A1KDM4EKMT2AGAAMAPT | |
| SCHEMBL1490750 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857387-A1 | Process for manufacturing 1,6-dihydro-6-oxo-4-pyridazine carboxylic acid | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-04-08 | — | — | EP | disclosed |
| EP-2857387-A1 | Process for manufacturing 1,6-dihydro-6-oxo-4-pyridazine carboxylic acid | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-04-08 | — | — | EP | disclosed |