Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | RGS12 | O14924 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | RARA | P10276 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16612276 | 0.98 | KMT2A (0.38) | KMT2AMEN1ALDH1A1HPGDCHRM2 | |
| SCHEMBL16612635 | 0.98 | KMT2A (0.38) | KMT2AMEN1ALDH1A1HPGDCHRM2 | |
| SCHEMBL16612447 | 0.83 | KMT2A (0.44) | KMT2AMEN1ALDH1A1HPGDCHRM2 | |
| SCHEMBL16612732 | 0.83 | KMT2A (0.44) | KMT2AMEN1ALDH1A1HPGDCHRM2 | |
| SCHEMBL5281905 | 0.74 | APOBEC3A (0.37) | KMT2AMEN1ALDH1A1HPGDCHRM2 | |
| SCHEMBL5944513 | 0.72 | APOBEC3A (0.40) | KMT2AMEN1ALDH1A1HPGDCHRM2 | |
| SCHEMBL814654 | 0.72 | MEN1 (0.52) | KMT2AMEN1ALDH1A1CHEK1KDR | |
| SCHEMBL21811989 | 0.70 | MEN1 (0.50) | KMT2AMEN1ALDH1A1CHEK1KDR | |
| SCHEMBL9064783 | 0.68 | ACHE (0.42) | ALDH1A1HPGD | |
| SCHEMBL12802229 | 0.67 | SMN1; SMN2 (0.53) | KMT2AMEN1HPGDKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857446-B1 | TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE | SUMITOMO RUBBER IND (JP) | 2018-03-07 | — | — | EP | disclosed |
| US-9790359-B2 | Tread rubber composition and pneumatic tire | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2017-10-17 | — | — | US | disclosed |
| US-20150099823-A1 | TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2015-04-09 | — | — | US | disclosed |
| EP-2857446-A1 | TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE | Sumitomo Rubber Industries, Ltd. (JP) | 2015-04-08 | — | — | EP | disclosed |