Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22279768 | 0.81 | BRD4 (0.46) | BRD4CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL1026647 | 0.81 | BRD4 (0.46) | BRD4CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL28009406 | 0.81 | BRD4 (0.46) | BRD4CHRNB2CHRNA4CHRNB4CHRNA3 | |
| Acetic Acid Methyl Ester SCHEMBL9151328 | 0.76 | BRD4 (0.42) | BRD4CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL11416871 | 0.76 | BRD4 (0.48) | BRD4CHRNB2CHRNA4CHRNB4CHRNA3 | |
| Propene SCHEMBL7744011 | 0.74 | BRD4 (0.40) | BRD4CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL16579361 | 0.70 | CHRNB2 (0.47) | BRD4CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL2153275 | 0.70 | BRD4 (0.43) | BRD4CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL872959 | 0.69 | — | — | |
| SCHEMBL6937734 | 0.68 | CHRNB2 (0.47) | BRD4CHRNB2CHRNA4CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857387-A1 | Process for manufacturing 1,6-dihydro-6-oxo-4-pyridazine carboxylic acid | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-04-08 | — | — | EP | claimed |
| EP-2857387-A1 | Process for manufacturing 1,6-dihydro-6-oxo-4-pyridazine carboxylic acid | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-04-08 | — | — | EP | disclosed |
| EP-2857387-A1 | Process for manufacturing 1,6-dihydro-6-oxo-4-pyridazine carboxylic acid | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-04-08 | — | — | EP | disclosed |
| EP-2857387-A1 | Process for manufacturing 1,6-dihydro-6-oxo-4-pyridazine carboxylic acid | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-04-08 | — | — | EP | disclosed |