Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 3/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.33 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1026647 | 0.91 | BRD4 (0.46) | BRD4CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL28009406 | 0.91 | BRD4 (0.46) | BRD4CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL22279768 | 0.91 | BRD4 (0.46) | BRD4CHRNB2CHRNA4CHRNB4CHRNA3 | |
| Acetic Acid Methyl Ester SCHEMBL9151328 | 0.86 | BRD4 (0.42) | BRD4CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL7744093 | 0.81 | PDE4A (0.37) | BRD4CHRNB2CHRNA4CHRNB4CHRNA3 | |
| Dodecanol SCHEMBL28693387 | 0.76 | SLC5A1 (0.41) | BRD4KMT2APDE4APDE4BPDE4C | |
| SCHEMBL16612384 | 0.74 | BRD4 (0.43) | BRD4CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL8262495 | 0.74 | CHRNB2 (0.43) | BRD4CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL28009383 | 0.74 | MAPK1 (0.39) | ACACBSCN8ASLC5A1 | |
| SCHEMBL2153275 | 0.74 | BRD4 (0.43) | BRD4CHRNB2CHRNA4CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0951468-A4 | SILICONE MONOMERS AND OLIGOMERS HAVING A CARBOXYL FUNCTIONAL GROUP THEREON | MONA INDUSTRIES INC (US) | 2001-06-06 | — | — | EP | disclosed |
| EP-0951468-A1 | SILICONE MONOMERS AND OLIGOMERS HAVING A CARBOXYL FUNCTIONAL GROUP THEREON | MONA INDUSTRIES, INC. (US) | 1999-10-27 | — | — | EP | disclosed |
| WO-1998022478-A1 | SILICONE MONOMERS AND OLIGOMERS HAVING A CARBOXYL FUNCTIONAL GROUP THEREON | MONA INDUSTRIES, INC. (US) | 1998-05-28 | — | — | WO | disclosed |