Acetic Acid

Acetic Acid

SCHEMBL1661239

CC(=O)[O-].CCCCCc1[nH]cc[n+]1CCCCC

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 3/20 0.37
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
RGS12 O14924 2/20 0.34
HSP90AA1 P07900 2/20 0.34
MAPK1 P28482 2/20 0.34
APAF1 O14727 1/20 0.34
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
HTT P42858 3/20 0.31
THRB P10828 2/20 0.31
KDM4E B2RXH2 2/20 0.31
NPC1 O15118 2/20 0.31
LMNA P02545 2/20 0.31
RAB9A P51151 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
USP2 O75604 1/20 0.31
RAD52 P43351 1/20 0.31
MCL1 Q07820 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL16712238 0.99 GPR84 (0.36) GPR84MEN1KMT2ARGS12HSP90AA1
Acetic Acid SCHEMBL29599422 0.93 HSP90AA1 (0.36) GPR84MEN1KMT2ARGS12HSP90AA1
Acetic Acid SCHEMBL1662200 0.93 GPR84 (0.32) GPR84
SCHEMBL4554670 0.89 KMT2A (0.37) GPR84MEN1KMT2ARGS12HSP90AA1
SCHEMBL18341989 0.88 KMT2A (0.40) GPR84MEN1KMT2ARGS12HSP90AA1
SCHEMBL18342039 0.88 KMT2A (0.40) GPR84MEN1KMT2ARGS12HSP90AA1
SCHEMBL4071944 0.88 KMT2A (0.40) GPR84MEN1KMT2ARGS12HSP90AA1
SCHEMBL5292633 0.88 KMT2A (0.40) GPR84MEN1KMT2ARGS12HSP90AA1
SCHEMBL5087442 0.88 KMT2A (0.40) GPR84MEN1KMT2ARGS12HSP90AA1
SCHEMBL2149021 0.88 KMT2A (0.40) GPR84MEN1KMT2ARGS12HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2486175-B1 A PROCESS OF MANUFACTURING LOW FIBRILLATING CELLULOSE FIBERS GRASIM IND LTD (IN) 2015-05-20 EP claimed
US-20120253030-A1 PROCESS FOR MANUFACTURING LOW-FIBRILLATING CELLULOSIC FIBER GRASIM INDUSTRIES LIMITED (IN) 2012-10-04 US claimed
US-20120253031-A1 PROCESS FOR MANUFACTURING LOW-FIBRILLATING CELLULOSIC FIBER GRASIM INDUSTRIES LIMITED (IN) 2012-10-04 US claimed
EP-2486062-A2 A PROCESS OF MANUFACTURING LOW-FIBRILLATING CELLULOSIC FIBERS Grasim Industries Limited (IN) 2012-08-15 EP claimed
EP-2486175-A2 A PROCESS OF MANUFACTURING LOW FIBRILLATING CELLULOSE FIBERS Grasim Industries Limited (IN) 2012-08-15 EP claimed
WO-2011048608-A2 A PROCESS OF MANUFACTURING LOW-FIBRILLATING CELLULOSIC FIBERS GRASIM INDUSTRIES LIMITED (IN) 2011-04-28 WO claimed
WO-2011048609-A2 A PROCESS OF MANUFACTURING LOW FIBRILLATING CELLULOSE FIBERS GRASIM INDUSTRIES LIMITED (IN) 2011-04-28 WO claimed
EP-2486175-B1 A PROCESS OF MANUFACTURING LOW FIBRILLATING CELLULOSE FIBERS GRASIM IND LTD (IN) 2015-05-20 EP disclosed
US-8952146-B2 Process for manufacturing low-fibrillating cellulosic fiber GRASIM INDUSTRIES LIMITED (IN) 2015-02-10 US disclosed
US-20120253031-A1 PROCESS FOR MANUFACTURING LOW-FIBRILLATING CELLULOSIC FIBER GRASIM INDUSTRIES LIMITED (IN) 2012-10-04 US disclosed
US-20120253030-A1 PROCESS FOR MANUFACTURING LOW-FIBRILLATING CELLULOSIC FIBER GRASIM INDUSTRIES LIMITED (IN) 2012-10-04 US disclosed
EP-2486062-A2 A PROCESS OF MANUFACTURING LOW-FIBRILLATING CELLULOSIC FIBERS Grasim Industries Limited (IN) 2012-08-15 EP disclosed
EP-2486175-A2 A PROCESS OF MANUFACTURING LOW FIBRILLATING CELLULOSE FIBERS Grasim Industries Limited (IN) 2012-08-15 EP disclosed
WO-2011048608-A2 A PROCESS OF MANUFACTURING LOW-FIBRILLATING CELLULOSIC FIBERS GRASIM INDUSTRIES LIMITED (IN) 2011-04-28 WO disclosed
WO-2011048609-A2 A PROCESS OF MANUFACTURING LOW FIBRILLATING CELLULOSE FIBERS GRASIM INDUSTRIES LIMITED (IN) 2011-04-28 WO disclosed