Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | RAD52 | P43351 | 2/20 | 0.37 |
| ▸ | RGS12 | O14924 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5085956 | 0.98 | KMT2A (0.40) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL5306990 | 0.98 | KMT2A (0.40) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL18342039 | 0.98 | KMT2A (0.40) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL5292633 | 0.98 | KMT2A (0.40) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL18341989 | 0.98 | KMT2A (0.40) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL17002622 | 0.98 | KMT2A (0.40) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL4071944 | 0.98 | KMT2A (0.40) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL5087442 | 0.98 | KMT2A (0.40) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL2149021 | 0.98 | KMT2A (0.40) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL5282913 | 0.98 | KMT2A (0.40) | KMT2AMEN1MAPTTP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11118308-B2 | Treatment of lignocellulosic biomass with ionic liquid | IP2IPO INNOVATIONS LIMITED (GB) | 2021-09-14 | — | — | US | disclosed |
| US-20180327969-A1 | Treatment | IMPERIAL INNOVATIONS LIMITED (GB) | 2018-11-15 | — | — | US | disclosed |
| US-9908901-B2 | Articles and methods comprising persistent carbenes and related compositions | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-03-06 | — | — | US | disclosed |
| US-9815793-B2 | Articles and methods comprising persistent carbenes and related compositions | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-11-14 | — | — | US | disclosed |
| US-20160355484-A1 | ARTICLES AND METHODS COMPRISING PERSISTENT CARBENES AND RELATED COMPOSITIONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-12-08 | — | — | US | disclosed |
| US-20160289248-A1 | ARTICLES AND METHODS COMPRISING PERSISTENT CARBENES AND RELATED COMPOSITIONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-10-06 | — | — | US | disclosed |
| US-9382210-B2 | Articles and methods comprising persistent carbenes and related compositions | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-07-05 | — | — | US | disclosed |
| US-20160040354-A1 | Treatment | IMPERIAL INNOVATIONS LIMITED (GB) | 2016-02-11 | — | — | US | disclosed |
| EP-2971333-A1 | TREATMENT | Imperial Innovations Ltd (GB) | 2016-01-20 | — | — | EP | disclosed |
| EP-2970569-A2 | PERSISTENT CARBENES AND RELATED COMPOSITIONS | Massachusetts Institute of Technology (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014160471-A2 | ARTICLES AND METHODS COMPRISING PERSISTENT CARBENES AND RELATED COMPOSITIONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2014-10-02 | — | — | WO | disclosed |
| WO-2014140643-A1 | TREATMENT | IMPERIAL INNOVATIONS LIMITED (GB) | 2014-09-18 | — | — | WO | disclosed |
| US-20140275555-A1 | ARTICLES AND METHODS COMPRISING PERSISTENT CARBENES AND RELATED COMPOSITIONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2014-09-18 | — | — | US | disclosed |
| EP-2118071-A2 | ALKYL H-PHOSPHONATES OF N,N'-DIALKYLIMIDAZOLIUMS AND OF QUATERNARY AMMONIUMS, AND USES THEREOF | Centre National de la Recherche Scientifique (CNRS) (FR) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008101881-A2 | ALKYL H-PHOSPHONATES OF N,N'-DIALKYLIMIDAZOLIUMS AND OF QUATERNARY AMMONIUMS, AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2008-08-28 | — | — | WO | disclosed |
| US-7220869-B2 | Brønsted acidic room temperature ionic liquids each having a N-protonated lactam cation and method for preparing the same | LANZHOU INSTITUTE OF CHEMICAL PHYSICS CHINESE ACADEMY OF SCIENCES (CN) | 2007-05-22 | — | — | US | disclosed |
| US-20070021604-A1 | Bronsted acidic room temperature ionic liquids each having a N-protonated lactam cation and method for preparing the same | LANZHOU INSTITUTE OF CHEMICAL PHYSICS CHINESE ACADEMY OF SCIENCES | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021604-A1 | Bronsted acidic room temperature ionic liquids each having a N-protonated lactam cation and method for preparing the same | SLC7A5, ALAD, SLC7A1 | KMT2A 4486/4885MEN1 600/4885MAPT 3317/4885 |
| US-20160040354-A1 | Treatment | DCXR, LCT, MGAM | KMT2A 1776/4885MEN1 4811/4885MAPT 307/4885 |
| US-20160355484-A1 | ARTICLES AND METHODS COMPRISING PERSISTENT CARBENES AND RELATED COMPOSITIONS | CES2, CNR2, CCRL2 | KMT2A 801/4885MEN1 2706/4885MAPT 3199/4885 |
| US-20160289248-A1 | ARTICLES AND METHODS COMPRISING PERSISTENT CARBENES AND RELATED COMPOSITIONS | CES2, CNR2, CCRL2 | KMT2A 801/4885MEN1 2706/4885MAPT 3199/4885 |
| US-20140275555-A1 | ARTICLES AND METHODS COMPRISING PERSISTENT CARBENES AND RELATED COMPOSITIONS | CES2, CNR2, CCRL2 | KMT2A 801/4885MEN1 2706/4885MAPT 3199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.