Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 5/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL485174 | 0.74 | USP2 (0.39) | USP2CYP2C19ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL24204144 | 0.74 | CYP11B2 (0.47) | USP2SMN1; SMN2 | |
| SCHEMBL16835509 | 0.72 | MGLL (0.35) | USP2CYP2C19ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL5895374 | 0.71 | CRBN (0.36) | MGLL | |
| SCHEMBL505075 | 0.69 | — | — | |
| SCHEMBL16464798 | 0.69 | USP2 (0.33) | USP2CYP2C19ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL933548 | 0.69 | USP2 (0.41) | USP2CYP2C19ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL15655085 | 0.69 | USP2 (0.36) | USP2CYP2C19ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL24203809 | 0.68 | MEN1 (0.33) | ALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL24203905 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857388-A1 | Azoles containing sulfone | Grünenthal GmbH (DE) | 2015-04-08 | — | — | EP | disclosed |