SCHEMBL16612482

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16803706	0.85	AKT1 (0.44)	POLBKDM4EALDH1A1NPC1SMN1; SMN2
	SCHEMBL16612304	0.85	POLB (0.48)	POLBKDM4EALDH1A1LMNAGRM2
	SCHEMBL15411967	0.85	POLB (0.49)	POLBKDM4EALDH1A1NPC1SMN1; SMN2
	SCHEMBL16613190	0.84	POLB (0.48)	POLBGRIN1GRIN2B
	SCHEMBL16611998	0.84	POLB (0.53)	POLBPDE10AGRIN1GRIN2B
	SCHEMBL14676724	0.83	POLB (0.48)	POLBKDM4EALDH1A1NPC1SMN1; SMN2
	SCHEMBL29431603	0.83	POLB (0.48)	POLBKDM4EALDH1A1NPC1SMN1; SMN2
	SCHEMBL20708853	0.82	POLB (0.45)	POLBKDM4EALDH1A1PDE10AHDAC1
	SCHEMBL15412037	0.81	POLB (0.46)	POLBALDH1A1SMN1; SMN2PDE10ALMNA
	SCHEMBL16611767	0.81	KDM4E (0.44)	POLBKDM4EALDH1A1SMN1; SMN2PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.