SCHEMBL16612304

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16803688	0.90	POLB (0.37)	POLBALDH1A1GAANPSR1LMNA
	SCHEMBL16612482	0.85	POLB (0.50)	POLBALDH1A1LMNAMAPTMET
	SCHEMBL10280988	0.83	POLB (0.49)	POLBGRIN1GRIN2B
	SCHEMBL16389593	0.82	ALDH1A1 (0.31)	ALDH1A1LMNAKMT2AMEN1PSMD14
	SCHEMBL16612240	0.82	POLB (0.48)	POLB
	SCHEMBL21925130	0.82	POLB (0.48)	POLBALDH1A1GAANPSR1LMNA
	SCHEMBL16613190	0.82	POLB (0.48)	POLBPTGS1PTGS2GRIN1GRIN2B
	SCHEMBL21925159	0.81	POLB (0.48)	POLBKMT2AMEN1
	SCHEMBL10280808	0.81	POLB (0.48)	POLB
	SCHEMBL10280699	0.81	POLB (0.48)	POLBALDH1A1GAANPSR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.