Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | FABP6 | P51161 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29872456 | 0.83 | MEN1 (0.45) | MEN1KMT2ATSHRALDH1A1RAB9A | |
| SCHEMBL785570 | 0.75 | ALDH1A1 (0.50) | MEN1KMT2ATSHRALDH1A1ACHE | |
| SCHEMBL571765 | 0.73 | GRIN2B (0.71) | GRIN2BMEN1KMT2AOPRM1OPRL1 | |
| SCHEMBL31682505 | 0.72 | GRIN2B (0.44) | GRIN2BMEN1KMT2AOPRM1OPRL1 | |
| SCHEMBL16612591 | 0.72 | FUCA1 (0.42) | GRIN2BMEN1KMT2AOPRM1OPRL1 | |
| SCHEMBL4371247 | 0.72 | GRIN2B (0.41) | GRIN2BMEN1KMT2AOPRM1OPRL1 | |
| SCHEMBL6098218 | 0.72 | PSEN1 (0.45) | OPRM1OPRL1IDO1ALDH1A1 | |
| SCHEMBL12061489 | 0.71 | CARM1 (0.45) | GRIN2BMEN1KMT2AOPRM1OPRL1 | |
| SCHEMBL7723868 | 0.70 | GRIN2B (0.66) | GRIN2BMEN1KMT2AOPRM1OPRL1 | |
| SCHEMBL12699061 | 0.70 | GRIN2B (0.41) | GRIN2BMEN1KMT2AOPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857388-A1 | Azoles containing sulfone | Grünenthal GmbH (DE) | 2015-04-08 | — | — | EP | disclosed |
| EP-2857388-A1 | Azoles containing sulfone | Grünenthal GmbH (DE) | 2015-04-08 | — | — | EP | disclosed |