Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | EBP | Q15125 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31368058 | 0.75 | PKM (0.46) | MEN1KMT2A | |
| SCHEMBL1644281 | 0.74 | GRIN2B (0.49) | FUCA1GRIN2BOPRM1OPRL1EBP | |
| SCHEMBL16386245 | 0.73 | GRIN2B (0.44) | FUCA1GRIN2BOPRM1OPRL1IDO1 | |
| SCHEMBL4371247 | 0.73 | GRIN2B (0.41) | FUCA1GRIN2BOPRM1OPRL1BCHE | |
| SCHEMBL14657362 | 0.72 | GRIN2B (0.62) | GRIN2BOPRM1OPRL1BCHEACHE | |
| SCHEMBL5246474 | 0.72 | GRIN2B (0.62) | GRIN2BOPRM1OPRL1BCHEACHE | |
| SCHEMBL16612528 | 0.72 | GRIN2B (0.43) | GRIN2BOPRM1OPRL1IDO1BCHE | |
| SCHEMBL12061489 | 0.72 | CARM1 (0.45) | GRIN2BOPRM1OPRL1BCHEACHE | |
| SCHEMBL19857422 | 0.71 | OPRM1 (0.44) | FUCA1GRIN2BOPRM1OPRL1EBP | |
| SCHEMBL12699061 | 0.71 | GRIN2B (0.41) | FUCA1GRIN2BOPRM1OPRL1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857388-A1 | Azoles containing sulfone | Grünenthal GmbH (DE) | 2015-04-08 | — | — | EP | disclosed |
| EP-2857388-A1 | Azoles containing sulfone | Grünenthal GmbH (DE) | 2015-04-08 | — | — | EP | disclosed |