Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL784990 | 0.85 | SMN1; SMN2 (0.43) | CYP2C19SMN1; SMN2 | |
| SCHEMBL803482 | 0.77 | OPRM1 (0.56) | OPRM1OPRL1GRIN2BTMEM97 | |
| SCHEMBL31682505 | 0.75 | GRIN2B (0.44) | OPRM1OPRL1SIGMAR1GRIN2BSMN1; SMN2 | |
| SCHEMBL15564665 | 0.73 | CYP2C9 (0.48) | OPRM1OPRL1CYP2C9CYP2C19SIGMAR1 | |
| SCHEMBL13819197 | 0.73 | FUCA1 (0.45) | OPRM1OPRL1SIGMAR1GRIN2B | |
| SCHEMBL30532010 | 0.73 | FUCA1 (0.45) | OPRM1OPRL1SIGMAR1GRIN2B | |
| SCHEMBL17652148 | 0.73 | FUCA1 (0.45) | OPRM1OPRL1SIGMAR1GRIN2B | |
| SCHEMBL3507722 | 0.73 | FUCA1 (0.45) | OPRM1OPRL1SIGMAR1GRIN2B | |
| SCHEMBL26319083 | 0.73 | FUCA1 (0.45) | OPRM1OPRL1SIGMAR1GRIN2B | |
| SCHEMBL13622714 | 0.72 | GRIN2B (0.45) | OPRM1OPRL1SIGMAR1GRIN2BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857388-A1 | Azoles containing sulfone | Grünenthal GmbH (DE) | 2015-04-08 | — | — | EP | disclosed |
| EP-2857388-A1 | Azoles containing sulfone | Grünenthal GmbH (DE) | 2015-04-08 | — | — | EP | disclosed |