Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BUB1 | O43683 | 1/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.33 |
| ▸ | NAT1 | P18440 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30284627 | 1.00 | NPC1 (0.35) | NPC1RAB9AS1PR1HDAC2KMT2A | |
| SCHEMBL16612574 | 1.00 | NPC1 (0.35) | NPC1RAB9AS1PR1HDAC2KMT2A | |
| SCHEMBL6544986 | 0.92 | CYP2C19 (0.39) | RAB9AKMT2ABUB1CYP3A4CYP2D6 | |
| SCHEMBL23931226 | 0.92 | CYP2C19 (0.39) | RAB9AKMT2ABUB1CYP3A4CYP2D6 | |
| SCHEMBL16612646 | 0.92 | CYP2C19 (0.39) | RAB9AKMT2ABUB1CYP3A4CYP2D6 | |
| SCHEMBL23931227 | 0.92 | CYP2C19 (0.39) | RAB9AKMT2ABUB1CYP3A4CYP2D6 | |
| SCHEMBL23931228 | 0.92 | CYP2C19 (0.39) | RAB9AKMT2ABUB1CYP3A4CYP2D6 | |
| SCHEMBL16612648 | 0.92 | CYP2C19 (0.39) | RAB9AKMT2ABUB1CYP3A4CYP2D6 | |
| SCHEMBL23931223 | 0.83 | CYP2C19 (0.41) | KMT2ACYP2C19LMNA | |
| SCHEMBL23931235 | 0.83 | APP (0.36) | NPC1RAB9AKMT2ACYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240415787-A1 | COMPOSITION FOR TREATING OR PREVENTING OBESITY OR OBESITY-ASSOCIATED LIVER DISEASE, COMPRISING VERBENONE DERIVATIVES | SHIN POONG PHARMACEUTICAL CO., LTD. (KR) | 2024-12-19 | — | — | US | claimed |
| EP-4397304-A1 | COMPOSITION FOR TREATING OR PREVENTING OBESITY OR OBESITY-ASSOCIATED LIVER DISEASE, COMPRISING VERBENONE DERIVATIVES | Shin Poong Pharmaceutical Co., Ltd. (KR) | 2024-07-10 | — | — | EP | claimed |
| CN-117897145-A | Composition for treating or preventing obesity or obesity-related liver diseases comprising verbenone derivatives | 韩国新丰制药株式会社 | 2024-04-16 | — | — | CN | claimed |
| US-10710951-B2 | Pharmaceutical composition containing verbenone derivative for treating or preventing neurodegenerative disease | SHIN POONG PHARMACEUTICAL CO., LTD. (KR) | 2020-07-14 | — | — | US | claimed |
| EP-2857007-B1 | PHARMACEUTICAL COMPOSITION CONTAINING VERBENONE DERIVATIVE FOR TREATING OR PREVENTING NEURODEGENERATIVE DISEASE | UNIV KOREA RES & BUS FOUND (KR) | 2018-03-28 | — | — | EP | claimed |
| US-20170166505-A1 | PHARMACEUTICAL COMPOSITION CONTAINING VERBENONE DERIVATIVE FOR TREATING OR PREVENTING NEURODEGENERATIVE DISEASE | SHIN POONG PHARMACEUTICAL CO., LTD. (KR) | 2017-06-15 | — | — | US | claimed |
| US-9603842-B2 | Pharmaceutical composition containing verbenone derivative for treating or preventing neurodegenerative disease | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2017-03-28 | — | — | US | claimed |
| US-20150148362-A1 | PHARMACEUTICAL COMPOSITION CONTAINING VERBENONE DERIVATIVE FOR TREATING OR PREVENTING NEURODEGENERATIVE DISEASE | SHIN POONG PHARMACEUTICAL CO., LTD. (KR) | 2015-05-28 | — | — | US | claimed |
| EP-2857007-A1 | PHARMACEUTICAL COMPOSITION CONTAINING VERBENONE DERIVATIVE FOR TREATING OR PREVENTING NEURODEGENERATIVE DISEASE | Korea University Research and Business Foundation (KR) | 2015-04-08 | — | — | EP | claimed |
| US-20240415787-A1 | COMPOSITION FOR TREATING OR PREVENTING OBESITY OR OBESITY-ASSOCIATED LIVER DISEASE, COMPRISING VERBENONE DERIVATIVES | SHIN POONG PHARMACEUTICAL CO., LTD. (KR) | 2024-12-19 | — | — | US | disclosed |
| EP-4397304-A1 | COMPOSITION FOR TREATING OR PREVENTING OBESITY OR OBESITY-ASSOCIATED LIVER DISEASE, COMPRISING VERBENONE DERIVATIVES | Shin Poong Pharmaceutical Co., Ltd. (KR) | 2024-07-10 | — | — | EP | disclosed |
| CN-117897145-A | Composition for treating or preventing obesity or obesity-related liver diseases comprising verbenone derivatives | 韩国新丰制药株式会社 | 2024-04-16 | — | — | CN | disclosed |
| US-10710951-B2 | Pharmaceutical composition containing verbenone derivative for treating or preventing neurodegenerative disease | SHIN POONG PHARMACEUTICAL CO., LTD. (KR) | 2020-07-14 | — | — | US | disclosed |
| EP-2857007-B1 | PHARMACEUTICAL COMPOSITION CONTAINING VERBENONE DERIVATIVE FOR TREATING OR PREVENTING NEURODEGENERATIVE DISEASE | UNIV KOREA RES & BUS FOUND (KR) | 2018-03-28 | — | — | EP | disclosed |
| CN-106977387-A | Nerve degenerative diseases treatment or prophylactic compositions containing verbenone derivatives | 高丽大学校产学协力团 | 2017-07-25 | — | — | CN | disclosed |
| US-20170166505-A1 | PHARMACEUTICAL COMPOSITION CONTAINING VERBENONE DERIVATIVE FOR TREATING OR PREVENTING NEURODEGENERATIVE DISEASE | SHIN POONG PHARMACEUTICAL CO., LTD. (KR) | 2017-06-15 | — | — | US | disclosed |
| CN-104768542-B | Pharmaceutical composition for treating or preventing neurodegenerative disease containing verbenone derivative | 高丽大学校产学协力团 | 2017-04-12 | — | — | CN | disclosed |
| US-9603842-B2 | Pharmaceutical composition containing verbenone derivative for treating or preventing neurodegenerative disease | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2017-03-28 | — | — | US | disclosed |
| US-20150148362-A1 | PHARMACEUTICAL COMPOSITION CONTAINING VERBENONE DERIVATIVE FOR TREATING OR PREVENTING NEURODEGENERATIVE DISEASE | SHIN POONG PHARMACEUTICAL CO., LTD. (KR) | 2015-05-28 | — | — | US | disclosed |
| EP-2857007-A1 | PHARMACEUTICAL COMPOSITION CONTAINING VERBENONE DERIVATIVE FOR TREATING OR PREVENTING NEURODEGENERATIVE DISEASE | Korea University Research and Business Foundation (KR) | 2015-04-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170166505-A1 | PHARMACEUTICAL COMPOSITION CONTAINING VERBENONE DERIVATIVE FOR TREATING OR PREVENTING NEURODEGENERATIVE DISEASE | CASP3, DCX, BAX | NPC1 351/4885RAB9A 3485/4885S1PR1 3770/4885 |
| US-10710951-B2 | Pharmaceutical composition containing verbenone derivative for treating or preventing neurodegenerative disease | CASP3, DCX, BAX | NPC1 351/4885RAB9A 3485/4885S1PR1 3770/4885 |
| US-20240415787-A1 | COMPOSITION FOR TREATING OR PREVENTING OBESITY OR OBESITY-ASSOCIATED LIVER DISEASE, COMPRISING VERBENONE DERIVATIVES | SMAD3, TGFB1, TGFB2 | NPC1 1142/4885RAB9A 4262/4885S1PR1 2881/4885 |
| US-20150148362-A1 | PHARMACEUTICAL COMPOSITION CONTAINING VERBENONE DERIVATIVE FOR TREATING OR PREVENTING NEURODEGENERATIVE DISEASE | CASP3, DCX, BAX | NPC1 351/4885RAB9A 3485/4885S1PR1 3770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.