Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 8/20 | 0.46 |
| ▸ | KYAT1 | Q16773 | 2/20 | 0.46 |
| ▸ | KYAT3 | Q6YP21 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.37 |
| ▸ | AR | P10275 | 5/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16613022 | 0.88 | AADAT (0.51) | AADATKYAT1KYAT3 | |
| SCHEMBL16613064 | 0.86 | AADAT (0.46) | AADATKYAT1KYAT3SLC22A12 | |
| SCHEMBL3786050 | 0.85 | AADAT (0.48) | AADATKYAT1KYAT3 | |
| SCHEMBL3776005 | 0.85 | AADAT (0.50) | AADATKYAT1KYAT3 | |
| SCHEMBL3778827 | 0.83 | AADAT (0.53) | AADATKYAT1KYAT3 | |
| SCHEMBL16612975 | 0.83 | AADAT (0.52) | AADATKYAT1KYAT3SLC22A12 | |
| SCHEMBL3779412 | 0.82 | AADAT (0.50) | AADATKYAT1KYAT3 | |
| SCHEMBL3779699 | 0.82 | AADAT (0.45) | AADATKYAT1KYAT3 | |
| SCHEMBL3779639 | 0.81 | AADAT (0.53) | AADATKYAT1KYAT3 | |
| SCHEMBL3779729 | 0.80 | AADAT (0.52) | AADATKYAT1KYAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443092-B1 | BICYCLIC AND TRICYCLIC COMPOUNDS AS KAT II INHIBITORS | PFIZER (US) | 2015-04-08 | — | — | EP | disclosed |