Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 12/20 | 0.52 |
| ▸ | KYAT3 | Q6YP21 | 3/20 | 0.52 |
| ▸ | KYAT1 | Q16773 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.38 |
| ▸ | DCK | P27707 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3779699 | 0.86 | AADAT (0.45) | AADATKYAT3KYAT1 | |
| SCHEMBL3773972 | 0.84 | AADAT (0.59) | AADATKYAT3KYAT1 | |
| SCHEMBL16613064 | 0.83 | AADAT (0.46) | AADATKYAT3KYAT1SLC22A12 | |
| SCHEMBL16612930 | 0.83 | AADAT (0.46) | AADATKYAT3KYAT1SLC22A12 | |
| SCHEMBL3785886 | 0.81 | AADAT (0.56) | AADATKYAT3KYAT1 | |
| SCHEMBL3776005 | 0.81 | AADAT (0.50) | AADATKYAT3KYAT1 | |
| SCHEMBL6763330 | 0.81 | AADAT (0.56) | AADATKYAT3KYAT1 | |
| SCHEMBL3774699 | 0.81 | AADAT (0.51) | AADATKYAT3KYAT1 | |
| SCHEMBL16612957 | 0.80 | GPR119 (0.39) | AADATKYAT3KYAT1SLC22A12 | |
| SCHEMBL3784051 | 0.77 | AADAT (0.43) | AADATKYAT3KYAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443092-B1 | BICYCLIC AND TRICYCLIC COMPOUNDS AS KAT II INHIBITORS | PFIZER (US) | 2015-04-08 | — | — | EP | disclosed |