Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL371748 | 0.77 | CALM1 (0.46) | CALM1HTR2AMEN1KMT2AHSD17B10 | |
| SCHEMBL10947990 | 0.75 | CALM1 (0.44) | CALM1HTR2AMEN1KMT2AHSD17B10 | |
| SCHEMBL27904505 | 0.75 | CALM1 (0.44) | CALM1HTR2AALDH1A1MEN1KMT2A | |
| SCHEMBL7211474 | 0.73 | EDNRB (0.48) | CALM1HTR2ABCL2BCL2L1 | |
| SCHEMBL5117305 | 0.72 | BCL2 (0.44) | CALM1HTR2AMEN1KMT2AHSD17B10 | |
| SCHEMBL30979860 | 0.72 | MAPK8 (0.54) | ALDH1A1KMT2AUSP2HSD17B10BCL2 | |
| SCHEMBL15877228 | 0.71 | PTPRC (0.54) | BCL2BCL2L1NPSR1 | |
| SCHEMBL29049113 | 0.71 | CALM1 (0.39) | CALM1HTR2AMEN1KMT2ABCL2 | |
| SCHEMBL972711 | 0.69 | CALM1 (0.69) | CALM1HTR2AMEN1KMT2AHSD17B10 | |
| SCHEMBL28362526 | 0.69 | HTR2A (0.56) | CALM1HTR2AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2665744-B1 | MACROCYCLIC COMPOUNDS WITH A HYBRID PEPTIDIC/NON-PEPTIDIC BACKBONE AND METHODS FOR THEIR PREPARATION | UNIV ROCHESTER (US) | 2015-04-08 | — | — | EP | claimed |