Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 16/20 | 0.55 |
| ▸ | KYAT3 | Q6YP21 | 4/20 | 0.55 |
| ▸ | KYAT1 | Q16773 | 3/20 | 0.55 |
| ▸ | GOT1 | P17174 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3779609 | 0.83 | AADAT (0.54) | AADATKYAT3KYAT1GOT1NOTUM | |
| SCHEMBL4801687 | 0.80 | AADAT (0.59) | AADATKYAT3KYAT1GOT1 | |
| SCHEMBL14170038 | 0.80 | AADAT (0.59) | AADATKYAT3KYAT1GOT1 | |
| Hydrochloric Acid SCHEMBL7416859 | 0.79 | AADAT (0.58) | AADATKYAT3KYAT1GOT1 | |
| SCHEMBL7419579 | 0.73 | AADAT (0.51) | AADATKYAT3KYAT1GOT1NOTUM | |
| Hydrochloric Acid SCHEMBL1239293 | 0.73 | AADAT (0.51) | AADATKYAT3KYAT1GOT1 | |
| SCHEMBL9690349 | 0.73 | CCKBR (0.52) | AADATKYAT3KYAT1GOT1 | |
| SCHEMBL4985549 | 0.72 | AADAT (0.50) | AADATKYAT3KYAT1GOT1MEN1 | |
| SCHEMBL2955903 | 0.71 | AADAT (1.00) | AADATKYAT3KYAT1GOT1 | |
| SCHEMBL3773423 | 0.71 | AADAT (1.00) | AADATKYAT3KYAT1GOT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443092-B1 | BICYCLIC AND TRICYCLIC COMPOUNDS AS KAT II INHIBITORS | PFIZER (US) | 2015-04-08 | — | — | EP | disclosed |