Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.68 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.57 |
| ▸ | ECE1 | P42892 | 2/20 | 0.55 |
| ▸ | TACR1 | P25103 | 2/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.51 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.51 |
| ▸ | CHRNG | P07510 | 1/20 | 0.51 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.51 |
| ▸ | CHRND | Q07001 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16862451 | 0.95 | CTSL (0.72) | CTSLITGB3ITGA2BECE1TACR1 | |
| Hydrochloric Acid SCHEMBL16862483 | 0.94 | CTSL (0.70) | CTSLITGB3ITGA2BECE1TACR1 | |
| Trifluoroacetic Acid SCHEMBL16862471 | 0.91 | CTSL (0.67) | CTSLITGB3ITGA2BECE1TACR1 | |
| SCHEMBL1663171 | 0.91 | CTSL (0.71) | CTSLECE1TACR1CTSBCTSS | |
| SCHEMBL1661924 | 0.91 | CTSL (0.71) | CTSLECE1TACR1CTSBCTSS | |
| Trifluoroacetic Acid SCHEMBL28515718 | 0.90 | CTSL (0.66) | CTSLITGB3ITGA2BECE1TACR1 | |
| SCHEMBL27757961 | 0.89 | ITGB3 (0.66) | CTSLITGB3ITGA2BECE1MME | |
| SCHEMBL14421191 | 0.89 | ITGB3 (0.66) | CTSLITGB3ITGA2BECE1MME | |
| SCHEMBL21318267 | 0.88 | CTSL (0.69) | CTSLITGB3ITGA2BECE1SIRT2 | |
| SCHEMBL1661910 | 0.88 | CTSL (0.65) | CTSLECE1TACR1CTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048390-A2 | GADD45BETA TARGETING AGENTS | IMPERIAL INNOVATIONS LIMITED (GB) | 2011-04-28 | — | — | WO | claimed |
| WO-2011048390-A2 | GADD45BETA TARGETING AGENTS | IMPERIAL INNOVATIONS LIMITED (GB) | 2011-04-28 | — | — | WO | disclosed |